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首页> 外文期刊>Optics Letters >Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection
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Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection

机译：具有时分多路复用的多共振光纤传感器，用于多分析物检测

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摘要

A proof-of-concept multiwindow fiber-optic sensor utilizing multiple particle plasmon resonance (PPR) of silver nanoparticles and gold nanorods separately on two unclad portions of the fiber for multianalyte detection is demonstrated. The detection is based on intensity interrogation of multiple wavelengths by a single detector. Time division multiplexing is employed to modulate the illumination of dual-wavelength LEDs to induce PPRs for simultaneous real-time and label-free monitoring of two types of biomolecular interactions. Preliminary results reveal that a refractive index resolution of 9 × 10~(-6) RIU is achieved. Moreover, the measured intensities of two windows independently respond to their respective binding events. The potential of the sensor architecture with multiple sensing windows for cascaded, higher throughput, and multianalyte biochemical detection can be expected.
机译：证明了一种概念证明的多窗口光纤传感器，该传感器利用银纳米颗粒和金纳米棒的多粒子等离子体激元共振（PPR）分别在光纤的两个未覆盖部分上进行多分析物检测。该检测基于单个检测器对多个波长的强度询问。时分复用用于调制双波长LED的照明，以诱导PPR，以同时实时和无标记地监视两种类型的生物分子相互作用。初步结果表明，折射率分辨率为9×10〜（-6）RIU。而且，两个窗口的测量强度独立地响应于它们各自的结合事件。可以预期具有用于级联，更高通量和多种分析物生化检测的多个传感窗口的传感器架构的潜力。

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