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Fiber-optic catheter-based polarization-sensitive OCT for radio-frequency ablation monitoring

机译:基于光纤导管的极化敏感OCT,用于射频消融监测

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摘要

An all-fiber optic catheter-based polarization-sensitive optical coherence tomography system is demonstrated. A novel multiplexing method was used to illuminate the sample, splitting the light from a 58.5 kHz Fourier-domain mode-locked laser such that two different polarization states, alternated in time, are generated by two semiconductor optical amplifiers. A 2.3 mm forward-view cone-scanning catheter probe was designed, fabricated, and used to acquire sample scattering intensity and phase retardation images. The system was first verified with a quarter-wave plate and then by obtaining intensity and phase retardation images of high-birefringence plastic, human skin in vivo, and untreated and thermally ablated porcine myocardium ex vivo. The system can potentially in vivo image of the cardiac wall to aid radio-frequency ablation therapy for cardiac arrhythmias.
机译:演示了基于全光纤导管的偏振敏感光学相干断层扫描系统。一种新颖的多路复用方法用于照亮样品,将58.5 kHz傅立叶域锁模激光器发出的光分开,从而由两个半导体光放大器产生时间上交替的两个不同的偏振态。设计,制造了一个2.3毫米的前视锥形扫描导管探头,并用于获取样品的散射强度和相位延迟图像。该系统首先用四分之一波片验证,然后通过获得高双折射塑料,体内人皮肤以及离体未处理和热消融猪心肌的强度和相位延迟图像进行验证。该系统可以对心脏壁进行体内成像,以辅助射频消融治疗心律失常。

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