首页> 外文期刊>Critical reviews in analytical chemistry >Spectrophotometric Methods for the Determination of Fluoroquinolones: A Review
【24h】

Spectrophotometric Methods for the Determination of Fluoroquinolones: A Review

机译:分光光度法测定氟喹诺酮类药物的研究进展

获取原文
获取原文并翻译 | 示例
           

摘要

The majority of quinolones of clinical use belong to the subset of fluoroquinolones, which have a flu-oro group attached the central ring system, typically at the 6-position. Fluoroquinolones are widely used in human and veterinary medicine. In recent times there has been significant development in the field of fluoroquinolones and many new analogues have been synthesized. The clinical and pharmaceutical analysis of these drugs requires effective analytical procedures for quality control and pharmacodynamic and pharmacokinetic studies. In this review article, various spectrophotometric methods used for determination of fluoroquinolones have been covered. The methods include visible spectrophotometry, which is based on formation of ion-pair or charge transfer complexes, UV spectrophotometry and derivative spectrophotometry. The application of these methods for the determination of fluoroquinolones in pharmaceutical and real samples has also been discussed.
机译:临床上使用的大多数喹诺酮类药物属于氟喹诺酮类药物,它们的氟环基团附着在中央环系统上,通常在6位。氟喹诺酮类药物广泛用于人类和兽医学。近年来,在氟喹诺酮类领域中已经有了重大发展,并且已经合成了许多新的类似物。这些药物的临床和药物分析要求进行有效的分析程序,以进行质量控制以及药代动力学和药代动力学研究。在这篇综述文章中,涵盖了用于测定氟喹诺酮类化合物的各种分光光度法。所述方法包括可见分光光度法,其基于离子对或电荷转移络合物的形成,UV分光光度法和导数分光光度法。还讨论了这些方法在测定药物和实际样品中氟喹诺酮类药物中的应用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号