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Thermal Therapy, Part III: Ablation Techniques

机译:热疗法,第三部分:消融技术

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Ablative treatments are gaining increasing attention as an alternative to standard surgical therapies, especially for patients with contraindication or those who refuse open surgery. Thermal ablation is used in clinical applications mainly for treating heart arrhythmias, benign prostate hyperplasia, and nonoperable liver tumors; there is also increasing application to other organ sites, including the kidney, lung, and brain. Potential benefits of thermal ablation include reduced morbidity and mortality in comparison with standard surgical resection and the ability to treat nonsurgical patients. The purpose of this review is to outline and discuss the engineering principles and biological responses by which thermal ablation techniques can provide elevation of temperature in organs within the human body. Because of the individual problems associated with each type of treatment, a wide range of ablation techniques have evolved including cryoablation as well as ultrasound, radiofrequency (RF), microwave, and laser ablation. Aspects of each ablation technique, including mechanisms of action, equipment required, selection of eligible patients, treatment techniques, and patient outcomes are presented, along with a discussion of limitations of the techniques and future research directions.
机译:作为标准手术疗法的替代方法,烧蚀疗法越来越受到关注,特别是对于禁忌症患者或拒绝开放手术的患者。热消融在临床上主要用于治疗心律不齐,良性前列腺增生和不可手术的肝肿瘤。在其他器官部位,包括肾,肺和脑中的应用也越来越多。与标准的手术切除相比,热消融术的潜在益处包括降低了发病率和死亡率,并且能够治疗非手术患者。这篇综述的目的是概述和讨论热消融技术可以提供人体器官温度升高的工程原理和生物学响应。由于与每种类型的治疗相关的个体问题,已经发展了广泛的消融技术,包括冷冻消融以及超声,射频(RF),微波和激光消融。介绍了每种消融技术的各个方面,包括作用机理,所需的设备,合格患者的选择,治疗技术和患者结果,并讨论了该技术的局限性和未来的研究方向。

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