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Squamous cell carcinoma of the conjunctiva in patients with atopic eczema.

机译：特应性湿疹患者结膜鳞状细胞癌。

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PURPOSE To report squamous cell carcinoma (SCC) of the conjunctiva in patients with atopic eczema.METHODS A retrospective study of six patients with conjunctival SCC associated with atopic eczema. Clinical and pathologic records were reviewed.RESULTS Ten patients with conjunctival SCC were seen from October 1999 to May 2002 at the Department of Ophthalmology at the University of Essen. Six of 10 patients had also atopic eczema. These six patients were treated either with local excision and ocular surface reconstruction or proton beam radiotherapy. None of the patients had local recurrences or metastases.CONCLUSION Atopic eczema is a common dermatological disease. An association with conjunctival SCC has not been reported so far. Squamous cell carcinoma has also been found in patients with AIDS and other immunosuppressed individuals. The dysfunction of T lymphocytes found in these disorders might play a crucial role in the malignant transformation of conjunctival tissue. Because of the reported frequency of SCC, patients with atopic eczema should be monitored for abnormalities.
机译：目的对特应性湿疹患者结膜鳞状细胞癌（SCC）进行报告。方法：回顾性研究6例结膜性SCC伴特应性湿疹患者。结果从1999年10月至2002年5月在埃森大学眼科收治了10例结膜SCC患者。 10名患者中有6名也患有特应性湿疹。这六名患者接受了局部切除和眼表重建或质子束放射治疗。所有患者均无局部复发或转移。结论特应性湿疹是一种常见的皮肤病。到目前为止，尚未报告与结膜SCC的关联。在艾滋病患者和其他免疫抑制患者中也发现了鳞状细胞癌。在这些疾病中发现的T淋巴细胞功能异常可能在结膜组织的恶性转化中起关键作用。由于报告了SCC的频率，应监测特应性湿疹患者的异常情况。

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