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Diamond burr polishing for recurrent corneal erosions: results from a prospective randomized controlled trial.

机译:金刚石毛刺抛光治疗复发性角膜糜烂:前瞻性随机对照试验结果。

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PURPOSE: To evaluate the use of diamond burr polishing as an in-office treatment for recurrent corneal erosion (RCE). METHODS: A double-masked randomized controlled trial was conducted. Patients with RCE secondary to trauma or anterior basement membrane dystrophy underwent epithelial debridement (ED) or diamond burr superficial keratectomy (DBSK) at the slit lamp. Patients were followed up for 6 months, and the recurrence rates of RCE and visual outcomes were compared. RESULTS: Forty-eight eyes of 48 patients were recruited. The mean +/- SD age was 38.3 +/- 12.9 years. Twenty-five patients underwent DBSK, and 23 patients received ED alone. There was no significant difference in the baseline demographics between the 2 groups. Kaplan-Meier survival analysis showed significantly less major and minor recurrences and less need for repeated surgical interventions in the DBSK group compared with the ED group (P < 0.001). Eyes in the DBSK group also had significantly lower mean magnitude of astigmatism after treatment compared to the ED group (P = 0.021). CONCLUSION: Diamond burr polishing is a safe, convenient, and inexpensive treatment option for the management of RCE and resulted in better outcomes compared to simple epithelial debridement.
机译:目的:评估金刚石毛刺抛光作为复发性角膜糜烂(RCE)的办公室治疗方法的用途。方法:进行了双掩蔽随机对照试验。继发于外伤或前基底膜营养不良的RCE患者在裂隙灯处接受上皮清创术(ED)或金刚石毛刺浅表角膜切除术(DBSK)。对患者进行了6个月的随访,并比较了RCE的复发率和视觉效果。结果:招募了48名患者的48只眼。 +/- SD平均年龄为38.3 +/- 12.9岁。 25例患者接受DBSK治疗,而23例患者仅接受ED。两组之间的基线人口统计学无显着差异。与ED组相比,Kaplan-Meier生存分析显示DBSK组的主要和次要复发率显着降低,重复外科手术的需求也更少(P <0.001)。与ED组相比,治疗后DBSK组的眼睛平均散光度也显着降低(P = 0.021)。结论:金刚石毛刺抛光是一种安全,方便,廉价的治疗RCE的治疗方法,与简单的上皮清创术相比,结果更好。

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