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首页> 外文期刊>Cornea >Late-onset laser in situ keratomileusis-related corneal ulcer--a case series.
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Late-onset laser in situ keratomileusis-related corneal ulcer--a case series.

机译：迟发性激光原位角膜磨镶术相关的角膜溃疡-病例系列。

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摘要

PURPOSE: To report 4 cases of flap margin-related corneal ulcer that developed 5 years after laser in situ keratomileusis (LASIK) procedures. METHODS: We retrospectively documented the clinical and laboratory characteristics of all patients between 2004 and 2008 who presented with LASIK-related corneal ulcer that appeared >5 years postoperatively. The 4 patients who had this condition were 25-, 33-, 61-, and 62-year-old males. RESULTS: Two patients had cultures positive to Staphylococcus aureus and Streptococcus epidermidis. Two ulcers healed after standard fortified topical antibiotic regimen, 1 ulcer healed after treatment with moxifloxacin, and the fourth healed after treatment with lomefloxacin. All cases presented 5 years after the LASIK procedure. CONCLUSIONS: LASIK procedures can be associated with the risk of corneal infection even years later. The mechanism may be flap margin instability causing epithelial defense barrier disturbance.
机译：目的：报告4例在激光原位角膜磨镶术（LASIK）手术5年后发展的与皮瓣边缘相关的角膜溃疡的病例。方法：我们回顾性记录了2004年至2008年之间所有出现LASIK相关角膜溃疡且术后出现> 5年的患者的临床和实验室特征。患有这种情况的4名患者分别是25岁，33岁，61岁和62岁的男性。结果：2例患者培养对金黄色葡萄球菌和表皮链球菌呈阳性。在标准强化局部抗生素治疗后，有2例溃疡ed愈;用莫西沙星治疗后有1例溃疡愈合;在用洛美沙星治疗后有4例愈合。所有病例均在LASIK手术后5年提出。结论：LASIK手术可能甚至与多年后角膜感染的风险有关。其机制可能是皮瓣边缘不稳定引起上皮防御屏障障碍。

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