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首页> 外文期刊>Cornea >Severe keratopathy in patients with AIDS with undiagnosed lagophthalmos.
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Severe keratopathy in patients with AIDS with undiagnosed lagophthalmos.

机译：患有未确诊的眼睑炎的艾滋病患者的严重角膜病变。

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PURPOSE: To report 2 cases of severe keratopathy in patients with AIDS with delayed diagnosis of lagophthalmos. METHODS: Observational case report. RESULTS: The first patient presented with a corneal abscess attributed to old trauma. He responded poorly to topical treatment and suffered corneal penetration. Penetrating keratoplasty was performed, but persistent epithelial defects appeared. Finally, occult lagophthalmos was discovered. Topical ocular lubrication, eye occlusion, and lateral tarsorrhaphy were insufficient, and the graft became conjunctivalized. The second patient had corneal opacity and severe pannus in his right eye and mild punctate keratopathy in his left eye. The left cornea worsened despite treatment with lubricants. In an examination 2 weeks later, we detected a subtle lagophthalmos, which was complicated by upper eyelid retraction in the right eye. A bilateral upper blepharotomy improved the keratopathy. CONCLUSIONS: Patients with AIDS with severe weight loss can present with lagophthalmos because of adipose and muscular atrophy in the so-called wasting syndrome. Lagophthalmos in patients with AIDS can be difficult to detect. Clinically significant lagophthalmos is associated with ocular surface lesions in patients with AIDS with wasting syndrome.
机译：目的：报道2例艾滋病患者的严重角膜病变，并延迟诊断为眼睑炎。方法：观察病例报告。结果：首例患者因旧创伤而出现角膜脓肿。他对局部治疗反应不佳，并经历了角膜穿透。进行了穿透性角膜移植术，但出现了持续的上皮缺损。最终，发现了隐匿性眼科动物。局部眼部润滑，眼闭塞和侧睑漏气不足，并且移植物结膜化。第二例患者的右眼角膜混浊，严重的pan肌，左眼轻度点状角膜病变。尽管使用润滑剂进行治疗，但左角膜仍恶化。在2周后的检查中，我们发现了一个细小的眼睑滑膜炎，并伴有右眼的上眼睑收缩。双侧上睑睑球切开术改善了角膜病变。结论：患有严重体重减轻的艾滋病患者由于所谓的消瘦综合症中的脂肪和肌肉萎缩而可出现眼睑炎。艾滋病患者的眼睑炎可能难以发现。患有浪费综合征的AIDS患者的眼表病变与临床上显着的腹泻有关。

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