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KeraRing intrastromal corneal ring segments for correction of keratoconus.

机译:KeraRing基质内角膜环段用于圆锥角膜矫正。

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PURPOSE: Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS: Retrospective case series descriptive study of 43 patients (55 eyes) with keratoconus who underwent KeraRing implantation from February 2008 to June 2009. Patients who had intraoperative or postoperative complications and/or did not complete at least 6 months of follow-up were excluded. All patients underwent complete ophthalmologic examinations that included measurement of the uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, and keratometry before and 2 days, 2 weeks, 1 month, and 3 and 6 months after surgery. The ring segments were chosen based on a nomogram from the manufacturer. RESULTS: Six months postoperatively, the mean UCVA increased significantly (P < 0.05) from 0.10 +/- 0.11 to 0.32 +/- 0.25 and the mean BSCVA increased from 0.36 +/- 0.23 to 0.57 +/- 0.24 (P < 0.05). The mean spherical refractive error significantly (P < 0.05) improved from -4.85 +/- 2.90 diopters (D) to -1.89 +/- 2.68 D, and the mean cylindrical refractive error significantly (P < 0.05) improved from -3.65 +/- 1.70 D to -2.60 +/- 1.62 D. The mean spherical equivalent significantly (P < 0.05) decreased from -6.68 +/- 2.93 D to -3.19 +/- 2.75 D, and the mean keratometry value decreased from 51.83 +/- 4.14 D to 47.27 +/- 3.68 D. The improvement in the UCVA and BSCVA continued over the 6-month postoperative period, but significant changes occurred only during the first 3 months. These changes occurred in patients with all grades of keratoconus. CONCLUSIONS: KeraRing implantation provided significant improvement in visual acuity, spherical equivalent, and keratometry results. This ICRS is an effective treatment for managing keratoconus and might delay or even avoid the need for penetrating keratoplasty.
机译:目的:角膜内角膜节段(ICRSs)是小的弧形植入物,越来越多地用作圆锥角膜患者的微创治疗。这项研究评估了ICRS类型的KeraRing植入物治疗圆锥角膜的有效性。方法:回顾性病例系列描述性研究对2008年2月至2009年6月接受KeraRing植入术的43例圆锥角膜患者(55眼)进行了研究。排除了术中或术后并发症和/或未完成至少6个月随访的患者。所有患者均接受了完整的眼科检查,包括未矫正视力(UCVA),最佳眼镜矫正视力(BSCVA),明显屈光度和角膜曲率的测量,分别在术后2天,2周,1个月以及3个月和6个月后进行手术。根据制造商的列线图选择环段。结果:术后六个月,平均UCVA从0.10 +/- 0.11显着增加(P <0.05)至0.32 +/- 0.25,平均BSCVA从0.36 +/- 0.23上升至0.57 +/- 0.24(P <0.05) 。平均球面屈光误差显着(P <0.05)从-4.85 +/- 2.90屈光度(D)改善至-1.89 +/- 2.68 D,并且平均柱面屈光误差显着(P <0.05)从-3.65 + / -1.70 D至-2.60 +/- 1.62D。平均球当量显着(P <0.05)从-6.68 +/- 2.93 D下降至-3.19 +/- 2.75 D,并且平均角膜曲率值从51.83 + / -4.14 D至47.27 +/- 3.68D。UCVA和BSCVA的改善在术后6个月内持续,但仅在头3个月内发生了显着变化。这些变化发生在所有级别的圆锥角膜患者中。结论:KeraRing植入显着改善了视敏度,球当量和角膜测量结果。该ICRS是治疗圆锥角膜的有效方法,可能会延迟甚至避免穿透性角膜移植的需要。

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