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首页> 外文期刊>Urology >Can computed tomography - Assisted virtual endoscopy be an innovative tool for detecting urethral tissue pathologies?
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Can computed tomography - Assisted virtual endoscopy be an innovative tool for detecting urethral tissue pathologies?

机译：计算机断层扫描-辅助虚拟内窥镜检查能否成为检测尿道组织病变的创新工具？

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Objective To test if virtual endoscopy (VE) enabled by 3-dimensional computed tomographic (CT) scanner with supporting software allows for practical clinical interrogation and evaluation of the urethral lumen and anatomy in an animal model. Methods Assessment of urethral anatomy and repair results was performed in 18 male beagles using conventional retrograde urethrography, CT-assisted retrograde urethography, and voiding urethrocystography. The image slices from these studies were processed using TeraRecon software to create a virtual representation of the urethra and compared with conventional urethrography and postmortem analysis of retrieved urethras for diagnostic assessment and correlation. Results CT-assisted VE showed the orientation, size, and gross morphology of urethral anatomy, including the lesions in all the 18 animals studied. The VE showed patent urethra in 12 dogs, stenosed urethra in 3 dogs, urethral diverticulum with stricture in 2 animals, and fistula in one. These findings correlated with those of conventional diagnostic methods. The findings of the voiding and retrograde virtual urethrocystoscopy studies were also comparable. Conclusion These results demonstrate that CT-assisted VE is able to identify the anatomic landmarks in an animal model. This allows for detection of the site of different pathologies and their relations to important structures such as urethral sphincters and the bladder neck. Digital imaging might be used to identify urethral pathologies with greater details and characterization of the lesions when compared with the conventional urethrocystography.
机译：目的测试具有支持软件的3D计算机断层扫描（CT）扫描仪支持的虚拟内窥镜（VE）是否可以对动物模型中的尿道内腔和解剖结构进行实际的临床检查和评估。方法使用常规逆行尿道造影，CT辅助逆行尿道造影和排尿尿道膀胱造影对18只雄性比格犬进行尿道解剖和修复结果评估。这些研究的图像切片使用TeraRecon软件进行处理，以创建尿道的虚拟表示，并与常规尿道造影和取回尿道的事后分析进行比较，以进行诊断评估和关联。结果CT辅助的VE显示尿道解剖结构的方向，大小和总体形态，包括所有18只动物的病变。 VE显示12只狗出现尿道上尿，3只狗出现狭窄的尿道，2只动物出现狭窄的尿道憩室，一只出现瘘管。这些发现与常规诊断方法相关。排尿和逆行虚拟膀胱镜检查研究的结果也具有可比性。结论这些结果表明CT辅助VE能够识别动物模型中的解剖标志。这允许检测不同病理的部位及其与重要结构的关系，例如尿道括约肌和膀胱颈。与常规尿道膀胱造影术相比，数字成像可用于识别更详细的尿道病变和病变特征。

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