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The characteristics of the stone and urine composition in Chinese stone formers: Primary report of a single-center results

机译：中国结石人群结石和尿液成分的特征：单中心结果的初步报告

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Objective To assess urine composition in Chinese patients with urolithiasis. Methods Five hundred seven Chinese patients with urolithiasis from our center in southern China were included in this study. Analysis of stone composition was performed using infrared spectrometry. From all patients, 24-hour urine samples were collected for analysis of urinary variables. Some ion activity product risk indices were also calculated. Results The major stone constituents in the 507 analyzed stones were as follows: calcium oxalate (78.3%), infection stone components (14.6%), uric acid (3.6%), and calcium phosphate (3.4%). Only 1 stone was composed of cystine (0.2%). Of all patients, 504 (99.4%) had 1 or several urinary metabolic abnormalities. Hypocitraturia was recorded in 93.9%, high sodium excretion in 58.6%, small urine volume in 45.6%, hyperoxaluria in 31.0%, hypercalciuria in 26.0%, hyperuricosuria in 19.3%, and hyperphosphaturia in 2.8%. Moreover, high sodium excretion was more frequent in men than women (59.2% vs 49.3%, P =.027), whereas hypercalciuria was more common in women (34.5% vs 20.4%, P <.001). High levels of urine sodium (187.7 ± 86.9 vs 179.8 ± 107.7 mmol/24h, P =.038) and phosphate (18.26 ± 8.36 vs 15.69 ± 11.14 mmol/24h, P <.001) were found in men than in women. Infection stones were significantly (P <.004) more common in women. Compared with noninfection stone formers, the occurrence of hypomagnesuria (P =.040) was more common in patients with infection stones. Conclusion The results of urinary risk factors for stone formation in this study might serve as a basis for design of recurrence prevention. It is of interest to note that some of the demonstrated abnormalities differ from that in reports from other countries.
机译：目的评估中国尿路结石患者的尿液成分。方法将来自中国南方地区的507例中国尿路结石患者纳入研究。使用红外光谱法分析石材组成。从所有患者中收集24小时尿液样本以分析尿量。还计算了一些离子活度产物风险指数。结果507块分析的结石的主要结石成分如下：草酸钙（78.3％），感染结石成分（14.6％），尿酸（3.6％）和磷酸钙（3.4％）。胱氨酸仅占1个结石（0.2％）。在所有患者中，有504名（99.4％）有1或几个泌尿代谢异常。低尿血症占93.9％，高钠排泄占58.6％，小尿量占45.6％，高草酸尿症占31.0％，高尿酸尿症占26.0％，高尿酸尿症占19.3％，高血尿症占2.8％。此外，男性高钠排泄比女性高（59.2％对49.3％，P = .027），而高钙尿症在女性中更为常见（34.5％对20.4％，P <.001）。男性尿液钠含量较高（187.7±86.9 vs 179.8±107.7 mmol / 24h，P = .038）和磷酸盐含量较高（18.26±8.36 vs 15.69±11.14 mmol / 24h，P <.001）。感染结石在女性中更为常见（P <.004）。与非感染性结石形成者相比，感染性结石患者低镁尿的发生率更高（P = .040）。结论本研究中尿结石形成的尿路危险因素的结果可为预防复发设计提供依据。值得一提的是，一些已证明的异常情况与其他国家的报告有所不同。

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