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Effect of chain length and asymmetry on material properties of bilayer membranes - art. no. 244901

机译:链长和不对称性对双层膜材料性能的影响-艺术没有。 244901

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Dissipative particle dynamics is used to extract the material parameters (bending and area stretch moduli) of a bilayer membrane patch. Some experiments indicate that the area stretch modulus of lipid vesicles varies little as the chain length of the lipids composing the bilayer increases. Here we show that making the interactions between the hydrophilic head groups of the model amphiphiles proportional to the hydrophobic tail length reproduces the above result for the area stretch modulus. We also show that the area stretch modulus of bilayers composed of amphiphiles with the same number of tail beads but with asymmetric chains is less than that of bilayers with symmetric chains. The effects on the bilayer density and lateral stress profiles of changes to the amphiphile architecture are also presented. (c) 2005 American Institute of Physics.
机译:耗散粒子动力学用于提取双层膜贴剂的材料参数(弯曲和面积拉伸模量)。一些实验表明,随着组成双层的脂质的链长增加,脂质囊泡的面积拉伸模量变化很小。在这里,我们表明,使模型两亲物的亲水头基之间的相互作用与疏水尾长成正比,可以得出上述面积拉伸模量的结果。我们还显示,由具有相同数目尾巴珠但具有不对称链的两亲物组成的双层的面积拉伸模量小于具有对称链的双层的面积拉伸模量。还介绍了两亲结构改变对双层密度和侧向应力分布的影响。 (c)2005年美国物理研究所。

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