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首页> 外文期刊>The journal of physical chemistry, A. Molecules, spectroscopy, kinetics, environment, & general theory >Relationship between Activation Volume and Polymer Matrix Effects on Photochromic Performance: Bridging Molecular Parameter to Macroscale Effect
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Relationship between Activation Volume and Polymer Matrix Effects on Photochromic Performance: Bridging Molecular Parameter to Macroscale Effect

机译:激活量和聚合物基质对光致变色性能的影响之间的关系:桥接分子参数到宏观效应。

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摘要

A facile one-pot synthesis of protoberberines from readily accessible 1,2,3,4-tetrahydroisoquinoline-1-carbonitriles and 1,2-bis(bromomethyl)arenes is described. The reaction cascade comprises four consecutive transformations, all of which can be effected under a single set of conditions. Ten protoberberines, including the alkaloids pseudopalmatine and pseudoepiberberine, were prepared in yields up to 86% according to this strategy. No chromatographic purification of the products is required, and the route is devoid of any protecting group manipulations.
机译:描述了从容易获得的1,2,3,4-四氢异喹啉-1-腈和1,2-双(溴甲基)芳烃轻松合成一锅小ber碱的方法。反应级联包括四个连续的转化,所有这些转化都可以在一组条件下进行。根据该策略,制备了十种原小ber碱,包括生物碱假巴马汀和假小iber碱,收率高达86%。不需要色谱纯化产物,并且该路线没有任何保护基操纵。

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