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Influenza vaccine in pregnancy: Policy and research strategies

机译：孕妇流感疫苗：政策和研究策略

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Influenza vaccination in pregnancy reduces maternal illness, improves fetal outcomes, prevents influenza in the infant up to 6 months of age, and potentially improves long-term adult outcomes for the infant (table 1). These effects on four life stages are not widely known by policy makers, and we provide a summary with recommendations for policy and needed research. Influenza in healthy pregnant women has been recognised since 1918 to carry a two to five times increased risk of severe respiratory illness and admission to hospital compared with influenza in non-pregnant women. Increased influenza susceptibility in pregnancy and the availability of inactivated vaccine led to the recommendation in 1960 by US public health authorities that pregnant women should be a priority group for influenza immunisation (appendix).1 Canada, the UK, and nine other European countries have since adopted this policy. In 2012, WHO's Strategic Advisory Group of experts stated that the highest priority group for influenza vaccine is pregnant women, because both mother and infant benefit from a single antenatal dose (appendix). Results of many studies have shown that influenza vaccines are safe in pregnancy.
机译：怀孕期间的流感疫苗接种减少了产妇的疾病，改善了胎儿的结局，预防了6个月以下婴儿的流感，并有可能改善了婴儿的长期成人结局（表1）。这些对四个生命阶段的影响尚未为政策制定者所广泛了解，因此我们提供了有关政策建议和所需研究的摘要。自1918年以来，健康孕妇中的流感被认为与非孕妇中的流感相比，患严重呼吸道疾病和住院的风险增加了2至5倍。妊娠中流感易感性的增加和灭活疫苗的可用性导致美国公共卫生当局于1960年提出建议，将孕妇作为流感疫苗的优先人群（附录）。1加拿大，英国和其他9个欧洲国家通过了这项政策。 2012年，世卫组织战略咨询专家组指出，流感疫苗的最高优先群体是孕妇，因为母婴均受益于一次产前剂量（附录）。许多研究结果表明，流感疫苗在怀孕期间是安全的。

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