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Status of human monkeypox: clinical disease, epidemiology and research

机译:人类猴痘的现状:临床疾病,流行病学和研究

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摘要

Monkeypox, a vesiculo-pustular rash illness, was initially discovered to cause human infection in 1970 through the World Health Organization (WHO)-sponsored efforts of the Commission to Certify Smallpox Eradication in Western Africa and the Congo Basin. The virus had been discovered to cause a nonhuman primate rash illness in 1958, and was thus named monkeypox. The causative agents of monkeypox and smallpox diseases both are species of Orthopoxvirus. Orthopoxvirus monkeypox, when it infects humans asan epizootic, produces a similar clinical picture to that of ordinary human smallpox. Since 1970, extensive epidemiology, virology, ecology and public health research has enabled better characterization of monkeypox virus and the associated human disease. This work reviews the progress in this body of research, and reviews studies of this "newly" emerging zoonotic disease.
机译:猴痘是一种水疱-脓疱疹病,最初是在世界卫生组织(WHO)赞助的西非和刚果盆地消灭天花认证委员会的努力下于1970年发现的,可引起人类感染。该病毒于1958年被发现引起一种非人类灵长类皮疹疾病,因此被命名为猴痘。猴痘和天花病的病原均属于正痘病毒。正痘病毒猴痘在作为人类流行病感染人类时,会产生与普通人类天花相似的临床症状。自1970年以来,广泛的流行病学,病毒学,生态学和公共卫生研究使猴痘病毒及其相关人类疾病的特征得以更好地表征。这项工作回顾了这一研究的进展,并回顾了这种“新的”新兴人畜共患病的研究。

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