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首页> 外文期刊>Vaccine >Influenza vaccine effectiveness among adult patients in a University of Lyon hospital (2004-2009).
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Influenza vaccine effectiveness among adult patients in a University of Lyon hospital (2004-2009).

机译:里昂大学医院成年患者的流感疫苗有效性(2004-2009年)。

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The aim of this study was to estimate influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza among hospitalized patients. A case-control investigation was based on the prospective surveillance of influenza-like illness (ILI) during five flu seasons. We compared influenza-positive cases and influenza-negative controls. Unadjusted overall IVE was 62% (95% confidence interval 24% to 81%). We found that IVE was lower during the 2004-05 flu season (11%; 95% CI -232% to 76%) when the vaccine and circulating viruses were mismatched. Expansion of the study to other hospitals could provide IVE estimates earlier in the season, for different age groups and emerging virus strains.
机译:这项研究的目的是评估住院患者中针对实验室确认的流感的流感疫苗效力(IVE)。病例对照调查基于五个流感季节期间对类流感的前瞻性监测。我们比较了流感阳性病例和阴性阴性对照。未经调整的总体IVE为62%(95%置信区间为24%至81%)。我们发现,当疫苗和正在传播的病毒不匹配时,在2004-05流感季节,IVE较低(11%; 95%CI -232%至76%)。将研究扩展到其他医院可以为不同年龄组和新出现的病毒株在本季节早期提供IVE估计。

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