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Global Prevention and Management of Human Papillomavirus Related Diseases: The Pressing Challenges and the Compelling Opportunities Foreword

机译:人类乳头瘤病毒相关疾病的全球预防和管理:紧迫的挑战和令人信服的机会前言

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Where are we now We have gained tremendous knowledge about human papillomaviruses (HPV) and their interactions with host cells, tissues and immune systems; have validated and implemented strategies for prophylactic vaccination against HPV infections; have developed increasingly sensitive and specific molecular diagnostic tools; and substantially increased global awareness of HPV and the many associated diseases of women, men, and children. In so doing, we have come up against new and daunting challenges: costs of HPV prevention and medical care, the implementation of what is technically possible, the diverse societal standards around the globe concerning reproductive health, and the very wide ranges of national economic capabilities and health care systems. HPV is one of the very few agents of infectious diseases and carcinogenesis where the emerging opportunities for prevention have encountered some socio-political resistance, the nature of which depends on country and culture. In addition, there has been too quick a willingness for policy makers, funding agencies and corporate stakeholders to discount the need for significant new developments, particularly in the arenas of therapeutics and affordable interventions. An expanded repertoire of health care options is urgently needed to bring HPV under short term management and long-term elimination. Thus, we are at cross-roads that will require thoughtful discussions, compassionate decisions and concerted actions.
机译:我们现在在哪里我们已经获得了有关人乳头瘤病毒(HPV)及其与宿主细胞,组织和免疫系统的相互作用的丰富知识;已经验证并实施了针对HPV感染的预防性疫苗接种策略;已经开发了越来越灵敏和特定的分子诊断工具;并大大提高了全球对HPV以及妇女,男子和儿童的许多相关疾病的认识。这样做,我们面临着新的艰巨挑战:预防HPV和医疗服务的成本,技术上可行的实施,全球范围内有关生殖健康的各种社会标准以及广泛的国家经济能力和医疗保健系统。 HPV是极少数的传染病和致癌因素之一,在这些疾病中,新兴的预防机会遇到了一些社会政治阻力,其性质取决于国家和文化。此外,决策者,供资机构和公司利益相关者的意愿太快了,无法满足重大新进展的需求,特别是在治疗和负担得起的干预领域。迫切需要扩大医疗保健选择范围,以使HPV受到短期管理和长期淘汰。因此,我们处在十字路口,需要进行认真的讨论,富有同情心的决定和一致行动。

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  • 来源
    《Vaccine》 |2012年第5期|共4页
  • 作者

    Broker Thomas R.;

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