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首页> 外文期刊>Vaccine >Quantitative evaluation of the effect of the hepatitis B vaccine based on the HBsAg- and anti-HBs-positive rates in the Chinese population over the last 33 years
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Quantitative evaluation of the effect of the hepatitis B vaccine based on the HBsAg- and anti-HBs-positive rates in the Chinese population over the last 33 years

机译：根据过去33年中中国人群的HBsAg和抗HBs阳性率对乙型肝炎疫苗的效果进行定量评估

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Objective: The purpose of the study was to quantitatively evaluate the effect of the hepatitis B vaccine based on 33 years of data published on the HBsAg- and anti-HBs-positive rates. Methods: All data were obtained from studies in published Chinese scientific journals from 1977 to 2009. The HBsAg- or anti-HBs-positive rate over a certain observation period was presented. Results: When the anti-HBs-positive rate was low, the ability of anti-HBs to control the HBsAg-positive rate is not apparent. When the anti-HBs level is high, the ability of anti-HBs to control the HBsAg-positive rate increases gradually, and a linear relationship was observed between the HBsAg-positive rate and the anti-HBs-positive rate. However, the rate of decrease of HBsAg positivity was markedly higher than the theoretical rate. Conclusion: The effect of other known or unknown factors, in addition to the vaccination campaign, could have contributed to the decrease in the prevalence of HBV infection. (C) 2012 Elsevier Ltd
机译：目的：本研究的目的是根据33年来有关HBsAg和抗HBs阳性率的数据定量评估乙型肝炎疫苗的效果。方法：所有数据均摘自1977年至2009年在中国发表的科学期刊上的研究。提出了在一定观察期内的HBsAg或抗HBs阳性率。结果：当抗HBs阳性率较低时，抗HBs控制HBsAg阳性率的能力不明显。当抗HBs水平高时，抗HBs控制HBsAg阳性率的能力逐渐增加，并且观察到HBsAg阳性率与抗HBs阳性率之间存在线性关系。但是，HBsAg阳性的降低率明显高于理论值。结论：除接种疫苗运动外，其他已知或未知因素的影响也可能有助于降低HBV感染率。 （C）2012爱思唯尔有限公司

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