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A qualitative study investigating knowledge and attitudes regarding human papillomavirus (HPV) and the HPV vaccine among parents of immunosuppressed children

机译：一项定性研究，研究免疫抑制儿童父母对人乳头瘤病毒（HPV）和HPV疫苗的知识和态度

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Barriers influencing the willingness of parents to vaccinate immunocompetent children include a lack of knowledge about human papillomavirus (HPV) and low perception of risk regarding their child's acquisition of HPV infection. However, it cannot be assumed that the facilitators and barriers of HPV vaccination are the same for parents/guardians of children who are immunocompromised, or who have chronic medical conditions. This study aimed to document the knowledge and attitudes of parents/guardians of immunosuppressed children and adolescents towards HPV infection and the vaccine. A study using qualitative methods which incorporated 27 semi-structured interviews was undertaken with parents/guardians of immunosuppressed children vaccinated against HPV at three hospitals in two states of Australia. Thematic analysis revealed that while participants acknowledged that they had heard of HPV, they did not have a strong sense of what it actually was. The level of concern held about their child acquiring an HPV infection (prior to vaccination) ranged from ‘not at all’ to ‘extremely’. Some believed that their child was at increased risk of developing a severe HPV-related illness because of their underlying condition. The participants supported their child receiving the HPV vaccine, as they did not want to take a risk with a disease that may cause their child to return to hospital for treatment. The majority had little apprehension about the use of the HPV vaccine but expressed some concern that potential adverse effects would be more severe for immunosuppressed children. However, they stressed their belief in the safety of the vaccine and their trust in the child's health team. Our study results show that parents of children with impaired immunity would benefit from further information about the safety of the vaccine and about the important role of the vaccine for boys as well as girls.
机译：影响父母为有免疫能力的孩子接种疫苗的意愿的障碍包括对人乳头瘤病毒（HPV）的了解不足以及对孩子感染HPV感染的风险了解不足。但是，不能假定对于免疫力低下或患有慢性疾病的儿童的父母/监护人来说，HPV疫苗接种的促进因素和障碍是相同的。这项研究旨在证明免疫抑制的儿童和青少年的父母/监护人对HPV感染和疫苗的知识和态度。在澳大利亚两个州的三所医院中，对使用HPV疫苗的免疫抑制儿童的父母/监护人进行了定性研究，纳入了27个半结构化访谈。专题分析表明，尽管参与者承认自己听说过HPV，但对实际情况并不十分了解。他们的孩子对HPV感染（在接种疫苗之前）的关注程度从“完全没有”到“极度”不等。一些人认为，由于其潜在疾病，其孩子患严重HPV相关疾病的风险增加。参与者支持他们的孩子接受HPV疫苗，因为他们不想冒可能导致孩子返回医院接受治疗的疾病的风险。大多数人对使用HPV疫苗的担心很少，但对免疫抑制儿童的潜在不良反应更为严重表示关注。但是，他们强调了对疫苗安全性的信任以及对儿童健康团队的信任。我们的研究结果表明，免疫力受损儿童的父母将从有关疫苗安全性以及该疫苗对男孩和女孩的重要作用的进一步信息中受益。

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