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Chikungunya virus vaccines: Current strategies and prospects for developing plant-made vaccines

机译:基孔肯雅病毒疫苗:开发植物疫苗的当前策略和前景

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Chikungunya virus is an emerging pathogen initially found in East Africa and currently spread into the Indian Ocean Islands, many regions of South East Asia, and in the Americas. No licensed vaccines against this eminent pathogen are available and thus intensive research in this field is a priority. This review presents the current scenario on the developments of Chikungunya virus vaccines and identifies the use of genetic engineered plants to develop attractive vaccines. The possible avenues to develop plant-made vaccines with distinct antigenic designs and expression modalities are identified and discussed considering current trends in the field. (C) 2015 Elsevier Ltd. All rights reserved.
机译:基孔肯雅病毒是一种新兴病原体,最初发现于东非,目前传播到印度洋群岛,东南亚的许多地区以及美洲。没有针对这种突出病原体的许可疫苗,因此在这一领域进行深入研究是当务之急。这篇综述介绍了基孔肯雅病毒疫苗发展的当前情况,并确定了利用基因工程植物开发有吸引力的疫苗的方法。考虑到该领域的当前趋势,确定并讨论了开发具有独特抗原设计和表达方式的植物疫苗的可能途径。 (C)2015 Elsevier Ltd.保留所有权利。

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