Organometallic anticancer agents that interfere with cellular energy processes: A subtle approach to inducing cancer cell death

Nazarov A.A.; Gardini D.; Baquié M.; Juillerat-Jeanneret L.; Serkova T.P.; Shevtsova E.P.; Scopelliti R.; Dyson P.J.

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Organometallic anticancer agents that interfere with cellular energy processes: A subtle approach to inducing cancer cell death

机译：干扰细胞能量过程的有机金属抗癌剂：诱导癌细胞死亡的微妙方法

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Two hybrid compounds comprising an antimetastatic ruthenium-arene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed.

机译：已经制备了两种杂化化合物，它们包含与癌细胞中有氧糖酵解抑制作用的吲哚-3-羧酸衍生物束缚的抗转移性钌-芳烃片段，并在多种癌细胞系中进行了评估，包括高度相关的人胶质母细胞瘤细胞。观察到的两个成分之间的协同作用。

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《Dalton transactions: An international journal of inorganic chemistry》 |2013年第7期|共4页
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Nazarov A.A.; Gardini D.; Baquié M.; Juillerat-Jeanneret L.; Serkova T.P.; Shevtsova E.P.; Scopelliti R.; Dyson P.J.;
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1. Organometallic anticancer agents that interfere with cellular energy processes: A subtle approach to inducing cancer cell death [J] . Nazarov A.A., Gardini D., Baquié M., Dalton transactions: An international journal of inorganic chemistry . 2013,第7期

机译：干扰细胞能量过程的有机金属抗癌剂：诱导癌细胞死亡的微妙方法
2. The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. [J] . Sun Y, Rigas B Cancer research: The official organ of the American Association for Cancer Research, Inc . 2008,第20期

机译：硫氧还蛋白系统在人类结肠癌细胞中介导氧化还原诱导的细胞死亡：对抗癌剂作用机制的影响。
3. Addition of anticancer agents enhances freezing-induced prostate cancer cell death: implications of mitochondrial involvement. [J] . Clarke DM, Baust JM, Van Buskirk RG, Cryobiology: International Journal of Low Temperature Biology and Medicine . 2004,第1期

机译：抗癌药的添加会增强冷冻诱导的前列腺癌细胞死亡：线粒体受累的影响。
4. Oridonin: A promising cell death-inducing anticancer drug from China [C] . Zhang Wenjing, Huang Qilai, Hua Zi-Chun International symposium on pharmacogenomics and the regulation of drug metabolism enzymes and genes. . 2010

机译：冬凌草甲素：来自中国的一种有前途的诱导细胞死亡的抗癌药
5. Apoptosis as a mechanism of cell death by anticancer agents. [D] . Barry, Michael Alan. 1991

机译：凋亡是抗癌剂引起细胞死亡的一种机制。
6. The thioredoxin system mediates redox-induced cell death in human colon cancer cells: Implications for the mechanism of action of anticancer agents [O] . Yu Sun, Basil Rigas -1

机译：硫氧还蛋白系统介导人结肠癌细胞中氧化还原诱导的细胞死亡：对抗癌药作用机制的影响
7. The Thioredoxin System Mediates Redox-Induced Cell Death in Human Colon Cancer Cells: Implications for the Mechanism of Action of Anticancer Agents [O] . Yu Sun, Basil Rigas 2008

机译：硫昔林系统在人结肠癌细胞中介导氧化还原诱导的细胞死亡：对抗癌剂作用机制的影响

Organometallic anticancer agents that interfere with cellular energy processes: A subtle approach to inducing cancer cell death

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