ATP-gated P2X channels

Girdler G; Khakh BS

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ATP-gated P2X channels

机译：ATP门控P2X通道

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摘要

What are they? P2X channels are a family of cell-membrane cation channels which open within milliseconds of binding ATP. They are distinct from the other family of ATP receptors, the G-protein-coupled P2Y receptors, and also from other transmitter-gated ion channels. P2X channels are the third major family of mammalian transmitter-gated ion channels (Figure 1); they are similar in topology to amiloride-sensitive sodium channels.

机译：这些是什么？ P2X通道是一系列细胞膜阳离子通道，可在结合ATP的毫秒内打开。它们不同于其他的ATP受体家族，G蛋白偶联的P2Y受体，也不同于其他的传输器门控离子通道。 P2X通道是哺乳动物发射器门控离子通道的第三大家族（图1）;它们的拓扑结构与阿米洛利敏感的钠通道相似。

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《Current Biology: CB》 |2004年第1期|共1页
作者
Girdler G; Khakh BS;
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正文语种 eng
中图分类生物科学;
关键词
Molecular physiology; Receptors;

机译：分子生理学;受体;

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专利

1. Single channel properties of ATP-gated cation channels (P2X receptors) heterologously expressed in Chinese hamster ovary cells. [J] . Evans RJ Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1996,第3期

机译：在中国仓鼠卵巢细胞中异源表达的ATP门控阳离子通道（P2X受体）的单通道特性。
2. MAPPING "MISSING" CONFORMATIONS OF ATP-GATED P2X RECEPTOR ION CHANNELS [J] . Stavrou A., Schmid R., Evans R. J. Purinergic Signalling . 2018,第1aS1期

机译：映射“缺失”ATP门控P2X受体离子通道的构象
3. Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels [J] . Go Kasuya, Yuichiro Fujiwara, Mizuki Takemoto, Cell Reports . 2016,第4期

机译：ATP门控P2X受体通道的二价阳离子调制的结构见解。
4. Molecular Dissection of Purinergic P2X Receptor Channels [C] . STANKO S. STOJILKOVIC, MELANIJA TOMI?, MU-LAN HE, International Biophysics Symposium . 2005

机译：嘌呤能P2X受体通道的分子解剖
5. Cross-inhibition between P2X and nAChR ligand-gated ion channels in the enteric nervous system. [D] . Decker, Dima Alkawwas. 2009

机译：肠神经系统中P2X和nAChR配体门控离子通道之间的交叉抑制。
6. Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors) [O] . Damien S. K. Samways, Baljit S. Khakh, Sébastien Dutertre, 2011

机译：优先使用通畅的侧向门作为通往人ATP门控离子通道（P2X受体）孔的通道
7. Identification of a trafficking motif involved in the stabilization and polarization of P2X receptors. : trafficking motif of P2X ATP-gated channels [O] . Chaumont, Séverine, Jiang, Lin-Hua, Penna, Aubin, 2004

机译：鉴定涉及P2X受体稳定和极化的运输基序。：P2X ATP门控通道的运输主题

ATP-gated P2X channels

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