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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Spinach cultigen variation for tissue carotenoid concentrations influences human serum carotenoid levels and macular pigment optical density following a 12-week dietary intervention
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Spinach cultigen variation for tissue carotenoid concentrations influences human serum carotenoid levels and macular pigment optical density following a 12-week dietary intervention

机译:经过12周的饮食干预后,菠菜培养素的组织类胡萝卜素浓度变化会影响人血清类胡萝卜素水平和黄斑色素光密度

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Increasing intakes of carotenoid-rich plant foods can increase serum carotenoid concentrations and macular pigment optical density (MPOD) in most, but not all, individuals. Research objectives for this study were to (1) characterize tissue lutein (L) and beta-carotene (BC) concentrations in carotenoid-rich spinach (Spinacia oleracea L.) cultigens and (2) determine serum carotenoid and MPOD responses in human subjects consuming spinach cultigens differing in tissue L and BC concentrations. Thirteen spinach cultigens were evaluated for carotenoid accumulations over two consecutive growing seasons. 'Springer' (8.4 and 6.5 mg/100 g of fresh mass for L and BC, respectively) and 'Spinner' (12.1 and 9.2 mg/100 g of fresh mass for L and BC, respectively) spinach cultigens were selected for a dietary intervention study and represented low- and high-L concentrations. The high-L ('Spinner') and low- L ('Springer') spinach treatment groups consisted of 10 subject volunteers ingesting five 50-g spinach servings/week during a 12-week intervention. Average serum L concentrations increased by 22% (P = 0.07) from baseline (0.233 mu mol/L) to 12 weeks (0.297 mu mol/L) for subjects consuming low- L spinach. Subjects consuming high-L spinach showed increases of 33% (P = 0.04) in serum L from baseline (0.202 mu mol/L) to 12 weeks (0.300 mu mol/L). Average MPOD did not change for the low- L treatment group; however, subjects in the high-L group demonstrated increases (P = 0.02) in MPOD at the 30' eccentricity between baseline (0.343) and 12 weeks (0.374). This study demonstrates that serum carotenoid and MPOD are determined by L concentrations present in the spinach matrix. Results emphasize the role of cultigen selection among vegetable crops in determining phytochemical effects on human health.
机译:在大多数(但不是全部)个体中,富含类胡萝卜素的植物性食物摄入量的增加会增加血清类胡萝卜素的浓度和黄斑色素光密度(MPOD)。这项研究的研究目标是(1)表征富含类胡萝卜素的菠菜(Spinacia oleracea L.)栽培品种中组织叶黄素(L)和β-胡萝卜素(BC)的浓度,以及(2)确定食用此类食物的人类受试者的血清类胡萝卜素和MPOD反应菠菜的组织L和BC浓度不同。在连续两个生长季节中,对13个菠菜栽培品种的类胡萝卜素积累进行了评估。选择菠菜的'Springer'(L和BC分别为8.4和6.5 mg / 100 g新鲜质量)和'Spinner'(L和BC的分别为12.1和9.2 mg / 100 g新鲜质量)菠菜干预研究,代表低和高L浓度。高L('Spinner')和低L('Springer')菠菜治疗组由10名受试者志愿者组成,他们在12周的干预过程中每周摄入五份50克菠菜,每星期一次。食用低L菠菜的受试者的平均血清L浓度从基线(0.233μmol/ L)到12周(0.297μmol/ L)增加了22%(P = 0.07)。食用高L菠菜的受试者的血清L从基线(0.202μmol/ L)到12周(0.300μmol/ L)增加了33%(P = 0.04)。低L治疗组的平均MPOD没有变化。但是,高L组的受试者在基线(0.343)和12周(0.374)之间的30'偏心率下表现出MPOD升高(P = 0.02)。这项研究表明,血清类胡萝卜素和MPOD是由菠菜基质中的L浓度决定的。结果强调了在选择蔬菜作物中的栽培源在确定对人类健康的植物化学作用方面的作用。

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