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首页> 外文期刊>Journal of Applied Polymer Science >In vitro blood compatibility of modified PDMS surfaces as superhydrophobic and superhydrophilic materials
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In vitro blood compatibility of modified PDMS surfaces as superhydrophobic and superhydrophilic materials

机译：改性PDMS表面作为超疏水和超亲水材料的体外血液相容性

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The surface of polydimethylsiloxane rubber (PDMS) was irradiated by a CO2-pulsed laser. The irradiated surfaces were grafted by hydroxyethylmethacrylate phosphatidylcholine (HEMAPC) by using the preirradiation method. The laser-treated surfaces and HENIAPC-grafted PDMS surfaces were characterized by using a variety of techniques including ATR-FTIR spectroscopy, scanning electron microscopy (SEM), and wettability, which was measured by a water-drop contact angle. Different surfaces with different wettability were prepared. These surfaces, including untreated PDMS (hydrophobic), laser-treated PDMS (superhydrophobic), and HEMAPC-grafted surfaces (superhydrophilic), were used for a platelet adhesion study. Results from in vitro testing indicated that chemical structures, such as negative-charge polar groups and wettability, are important factors in blood compatibility of these surfaces and the superhydrophilic (the most wettable) and the superhydrophobic (the most unwettable) of modified PDMS surfaces have excellent blood compatibility compared to the unmodified PDMS. (C) 2003 Wiley Periodicals, Inc. [References: 28]
机译：聚二甲基硅氧烷橡胶（PDMS）的表面被CO2脉冲激光照射。通过使用预辐照方法，将辐照表面用甲基丙烯酸羟乙酯磷脂酰胆碱（HEMAPC）接枝。激光处理过的表面和HENIAPC接枝的PDMS表面使用多种技术进行了表征，包括ATR-FTIR光谱，扫描电子显微镜（SEM）和可湿性，这些技术通过水滴的接触角进行测量。制备具有不同润湿性的不同表面。这些表面，包括未处理的PDMS（疏水性），激光处理的PDMS（超疏水性）和HEMAPC接枝的表面（超亲水性），用于血小板粘附研究。体外测试结果表明，化学结构（例如负电荷极性基团和润湿性）是这些表面血液相容性的重要因素，改性PDMS表面的超亲水性（最易润湿）和超疏水性（最不润湿）具有与未经修饰的PDMS相比，血液相容性极佳。 （C）2003 Wiley Periodicals，Inc. [参考：28]

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