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Preparation and characterization of novel sodium alginate/chitosan two ply composite membranes

机译:新型海藻酸钠/壳聚糖两层复合膜的制备与表征

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Sodium alginate/chitosan (SA/CS) two ply composite membranes were prepared by casting and solvent evaporation technique. NaHCO3 was used as a porogen additive to form pores in the interior of the composite membranes and glycerol was introduced as a plasticizer. The water uptake capacity, mechanical strength, oxygen permeation property, and in vitro cytotoxicity were evaluated to test the feasibility to utilize the composite membranes for wound dressing. The average pore size, water uptake capacity, and oxygen permeation property of the composite membranes could be adjusted by the ratio of NaHCO3 in the SA solution. The SA/CS two ply composite membranes showed high water uptake capacity, suitable mechanical strength, excellent oxygen permeability, and good biocompatible. It indicates that the SA/CS two ply composite membranes are suitable for wound dressing application. It provides a simple but promising platform to fabricate wound dressing using natural polymers. (C) 2007 Wiley Periodicals, Inc.
机译:通过流延和溶剂蒸发技术制备了藻酸钠/壳聚糖(SA / CS)两层复合膜。 NaHCO3用作致孔剂添加剂,以在复合膜的内部形成孔,并引入甘油作为增塑剂。评估了其吸水能力,机械强度,氧气渗透性和体外细胞毒性,以测试将复合膜用于伤口敷料的可行性。复合膜的平均孔径,吸水量和透氧性能可以通过SA溶液中NaHCO3的比例来调节。 SA / CS两层复合膜显示出高吸水能力,合适的机械强度,优异的透氧性和良好的生物相容性。这表明SA / CS两层复合膜适合伤口敷料应用。它提供了一个简单但很有前途的平台,可以使用天然聚合物制造伤口敷料。 (C)2007 Wiley期刊公司

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