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首页> 外文期刊>Journal of Applied Polymer Science >Preparation of di-butyryl-chitin scaffolds by using salt leaching method for tissue engineering and their characteristics
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Preparation of di-butyryl-chitin scaffolds by using salt leaching method for tissue engineering and their characteristics

机译：盐溶法制备组织工程用二丁酰甲壳素支架及其特性

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摘要

Scaffolds are used as support material in treatment of damaged tissues such as cartilage and bone. With the help of scaffolds, damaged tissues can be cured in shorter period with less pain. Chitin is one of the most important scaffold materials curing the damaged tissues while providing a support for related part of the body during healing period. It is biocompatible and biodegradable; however it can not be solved by common solvents leading to the major drawback for this kind of applications. Therefore di-butyril-chitin (DBC), which is a chitin derivative and can be solved easily in solvents like acetone, ethanol, and methanol, is preferred for scaffold production instead of chitin. In this study, DBC scaffolds were produced for orthopedic applications and their structural and mechanical properties such as porosity, elasticity, compressibility, and strength were tested to confirm their suitability for such enduses. (C) 2008 Wiley Periodicals, Inc.
机译：支架用作治疗受损组织（如软骨和骨骼）的支撑材料。借助脚手架，可以在更短的时间内治愈受损的组织，减少痛苦。甲壳质是治疗受损组织的最重要的支架材料之一，同时在愈合期间为身体的相关部位提供支撑。具有生物相容性和可生物降解性;然而，普通溶剂无法解决该问题，这导致此类应用的主要缺点。因此，作为甲壳质衍生物并且可以容易地溶解在诸如丙酮，乙醇和甲醇等溶剂中的二丁甲壳质-甲壳质（DBC）代替甲壳质优选用于支架生产。在这项研究中，为骨科应用生产了DBC支架，并对其结构和机械性能（例如孔隙率，弹性，可压缩性和强度）进行了测试，以确认其适用于此类最终用途。 （C）2008 Wiley期刊公司

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