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Topography Characterization and Initial Cellular Interaction of Plasma-Based Ar+ Beam-Treated PDMS Surfaces

机译:等离子体基Ar +束处理过的PDMS表面的形貌表征和初始细胞相互作用

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Assuming that the existence of an ion-flow in the plasmavolume could strength the surface modifying effect, including its durability, a parallel plate reactor in reactive ion etching mode was employed to obtain surface modified PDMS with improved cellular interaction. The discharge power was varied at 100, 1200, and 2500 W to ensure varied ion-flow density. The changes in the surface topography were observed by SEM and AFM, and the Surface roughness was characterized by both: mean roughness, R-a, and root-mean-square, R-q. Time dependent water contact angle measurements were performed to control the durability of the hydrophilizing effect. Anisotropic etching, accompanied with decrease of the PDMS Surface roughness, was observed Lip to discharge power of 1200 W that turns in intense isotropic one, accompanied with a sharp increase of the surface roughness over 1200 W, most probably because of arise of reverse sputtered neutrals diffracting the main plasma Ar+ flow. Human fibroblasts were applied as in in vitro model to learn more about the initial cellular interaction of the modified surfaces and to identify the optimal treatment conditions. (C) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 111: 2637-2646,2009
机译:假设等离子体体积中存在离子流可以增强表面改性效果,包括其耐久性,则采用反应离子蚀刻模式的平行板反应器来获得具有改善的细胞相互作用的表面改性PDMS。放电功率在100、1200和2500 W时变化,以确保变化的离子流密度。用SEM和AFM观察表面形貌的变化,并用平均粗糙度R-a和均方根R-q来表征表面粗糙度。进行与时间有关的水接触角测量,以控制亲水作用的持久性。观察到各向异性刻蚀,伴随着PDMS表面粗糙度的降低,嘴唇放电功率为1200 W,这变成了强烈的各向同性,同时表面粗糙度在1200 W以上急剧增加,这很可能是由于反向溅射的中性线引起的衍射主等离子体Ar +流。将人成纤维细胞用作体外模型,以了解有关修饰表面的初始细胞相互作用的更多信息,并确定最佳治疗条件。 (C)2008 Wiley Periodicals,Inc. J Appl Polym Sci 111:2637-2646,2009

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