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首页> 外文期刊>Journal of Applied Polymer Science >Synthesis and antimicrobial activity of Schiff base of chitosan and acylated chitosan
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Synthesis and antimicrobial activity of Schiff base of chitosan and acylated chitosan

机译：壳聚糖和酰化壳聚糖席夫碱的合成及抑菌活性

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摘要

Chitosan, a biocompatible, biodegradable, nontoxic polymer, is prepared from chitin, which is the second most naturally occurring biopolymer after cellulose. Schiff base of chitosan, sorbyl chitosan, and p-aminobenzoyl chitosan were synthesized working under high-intensity ultrasound and their antimicrobial properties were analyzed against Escherichia coli, Staphylococcus aureus, and Aspergillus niger. The structures of the derivatives were characterized by FTIR spectroscopy and elemental analysis. The results of antimicrobial activities indicated that the antimicrobial activities of the derivatives increased with increasing the concentration. The antibacterial activity of schiff base of chitosan against E. coli was stronger, while acylated chitosan had better inhiting effect on S. aureus than others. It was also found that the antifungal activities of the derivatives were stronger than that of chitosan, and schiff base of chitosan was obviously superior to acylated chitosan.
机译：壳聚糖是一种生物相容性，可生物降解的无毒聚合物，是由几丁质制备的，几丁质是仅次于纤维素的第二天然生物质。合成了壳聚糖，山梨糖基壳聚糖和对氨基苯甲酰基壳聚糖的席夫碱，在高强度超声下工作，并分析了它们对大肠杆菌，金黄色葡萄球菌和黑曲霉的抗菌性能。通过FTIR光谱和元素分析表征衍生物的结构。抗菌活性的结果表明，衍生物的抗菌活性随浓度的增加而增加。壳聚糖席夫碱对大肠杆菌的抑菌作用较强，而酰化壳聚糖对金黄色葡萄球菌的杀伤作用优于其他菌株。还发现该衍生物的抗真菌活性强于壳聚糖，并且壳聚糖的席夫碱明显优于酰化壳聚糖。

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