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首页> 外文期刊>Journal of Applied Polymer Science >Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings
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Novel atmospheric plasma enhanced chitosan nanofiber/gauze composite wound dressings

机译：新型大气等离子体增强的壳聚糖纳米纤维/纱布复合伤口敷料

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摘要

Electrospun chitosan nanofibers were deposited onto atmospheric plasma treated cotton gauze to create a novel composite bandage with higher adhesion, better handling properties, enhanced bioactivity, and moisture management. Plasma treatment of the gauze substrate was performed to improve the durability of the nanofiber/gauze interface. The chitosan nanofibers were electrospun at 3-7% concentration in trifluoroacetic acid. The composite bandages were analyzed using peel, gelbo flex, antimicrobial assay, moisture vapor transmission rate, X-ray photoelectron spectroscopy (XPS), absorbency, and air permeability tests. The peel test showed that plasma treatment of the substrate increased the adhesion between nanofiber layers and gauze substrate by up to four times. Atmospheric plasma pretreatment of the gauze fabric prior to electrospinning significantly reduced degradation of the nanofiber layer due to repetitive flexing. The chitosan nanofiber layer contributes significantly to the antimicrobial properties of the bandage. Air permeability and moisture vapor transport were reduced due to the presence of a nanofiber layer upon the substrate. XPS of the plasma treated cotton substrate showed formation of active sites on the surface, decrease in carbon content, and increase in oxygen content as compared to the untreated gauze. Deposition of chitosan nanofibers also increased the absorbency of gauze substrate.
机译：将静电纺丝的壳聚糖纳米纤维沉积到大气等离子体处理过的棉纱布上，以创建一种新型的复合绷带，该绷带具有更高的附着力，更好的处理性能，增强的生物活性和湿度管理。对纱布基底进行等离子体处理以提高纳米纤维/纱布界面的耐久性。将壳聚糖纳米纤维以3-7％的浓度在三氟乙酸中进行电纺。使用剥离，凝胶弯曲，抗菌测定，湿气透过率，X射线光电子能谱（XPS），吸收性和透气性测试来分析复合绷带。剥离测试表明，对基材进行等离子体处理可将纳米纤维层与纱布基材之间的粘合力提高多达四倍。在电纺之前，对纱布进行大气等离子体预处理可显着降低由于重复挠曲而导致的纳米纤维层降解。壳聚糖纳米纤维层显着有助于绷带的抗菌性能。由于在基底上存在纳米纤维层，因此降低了透气性和湿气传输。与未处理的纱布相比，经等离子体处理的棉基材的XPS显示在表面形成了活性位点，碳含量降低，氧含量增加。壳聚糖纳米纤维的沉积也增加了纱布基质的吸收性。

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