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首页> 外文期刊>Journal of Applied Polymer Science >Antimicrobial Activity of Water Resistant Surface Coating from Catechol Conjugated Polyquaternary Amine on Versatile Substrates
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Antimicrobial Activity of Water Resistant Surface Coating from Catechol Conjugated Polyquaternary Amine on Versatile Substrates

机译：邻苯二酚共轭多季胺的耐水表面涂层在多种基质上的抗菌活性。

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摘要

Water resistant polymer with adhesive behavior is reported to exhibit long-term antimicrobial activities under diverse conditions. To obtain highly adhesive polymer with prolonged antimicrobial activities and catechol moiety, 2-chloro-3',4'-dihydroxyacetophenone (CCDP) has been quaternized to poly(dimethylaminoethyl methacrylate) (PDMA). Later, for gaining the antimicrobial effects, the polymer (CCDP-q-PDMA) was quaternized with 1-bromododecane (C12) [CCDP/C12-q-PDMA]. X-ray photoelectron spectroscopy rectified the quaternization and adhesion of the polymer onto different substrates. The CCDP/C12-q-PDMA coated substrates exhibited remarkable bacterial killing efficiency against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, after incubation for 24 h. The remarkable antimicrobial activities exhibited in aqueous medium at 60℃ for up to 60 days indicate the strong adhesiveness of CCDP/C12-q-PDMA on the substrate. Therefore, the synthesized polymer offers merit as a potential coating material, to protect a broad range of material from microbial contamination, for a prolonged period of time, under a highly stressed water environment.
机译：据报道，具有粘合性能的耐水聚合物在各种条件下均具有长期的抗菌活性。为了获得具有延长的抗菌活性和邻苯二酚部分的高粘性聚合物，已将2-氯-3'，4'-二羟基苯乙酮（CCDP）季铵化为聚（甲基丙烯酸二甲基氨基乙酯）（PDMA）。随后，为了获得抗菌效果，将聚合物（CCDP-q-PDMA）与1-溴十二烷（C12）[CCDP / C12-q-PDMA]季铵化。 X射线光电子能谱校正了聚合物的季铵化和粘附在不同基材上的特性。孵育24小时后，涂有CCDP / C12-q-PDMA的底物对革兰氏阳性金黄色葡萄球菌和革兰氏阴性大肠杆菌均表现出显着的细菌杀灭效率。在60℃的水性介质中长达60天显示出显着的抗菌活性，这表明CCDP / C12-q-PDMA在底材上具有很强的粘合力。因此，在高应力水环境下，合成的聚合物可作为一种潜在的涂层材料，在很长的一段时间内保护各种材料免受微生物污染。

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