• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Assessment of cell proliferation in knitting scaffolds with respect to pore-size heterogeneity, surface wettability, and surface roughness
【24h】

Assessment of cell proliferation in knitting scaffolds with respect to pore-size heterogeneity, surface wettability, and surface roughness

机译：根据孔径异质性，表面润湿性和表面粗糙度评估编织支架中的细胞增殖

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this study, various types of poly(epsilon-caprolactone) (PCL) knitting scaffolds were fabricated and analyzed to assess the cell-culturing characteristics of knitting scaffolds with respect to pore-size heterogeneity, surface wettability, and surface roughness. First, control knitting scaffolds were fabricated using 150-mu m-diameter PCL monofilaments. Using chloroform and NaOH, PCL knitting scaffolds with varying roughness, pore-size heterogeneity, and surface wettability were fabricated. Cell-culture assessments were performed on these six types of PCL knitting scaffolds. Saos-2 cells were used for cell assessments and cultured for 14 days on each scaffold. Consequently, heterogeneous pore-size distribution and high surface wettability were found to enhance cell proliferation in knitting scaffolds. In addition, for highly hydrophobic knitting scaffolds exhibiting water contact angles greater than 110 degrees, smaller surface roughness was found to enhance cell proliferation. According to this study, in the case of knitting scaffold, NaOH-treated knitting scaffold, without any control for the pore-size homogenization, could be a candidate as the optimal knitting scaffold. (c) 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42566.
机译：在本研究中，制造并分析了各种类型的聚（ε-己内酯）编织支架，以评估编织支架在孔径大小异质性，表面润湿性和表面粗糙度方面的细胞培养特性。首先，使用直径为150微米的PCL单丝制造对照编织支架。使用氯仿和NaOH，制造了具有不同粗糙度，孔径不均一性和表面润湿性的PCL编织支架。对这六种PCL编织支架进行了细胞培养评估。将Saos-2细胞用于细胞评估，并在每个支架上培养14天。因此，发现异质孔径分布和高表面润湿性可增强编织支架中的细胞增殖。另外，对于表现出水接触角大于110度的高疏水性编织支架，发现较小的表面粗糙度可增强细胞增殖。根据这项研究，在编织支架的情况下，无任何孔径均质控制的NaOH处理编织支架可能是最佳的编织支架。 （c）2015 Wiley Periodicals，Inc. J. Appl。 Polym。科学2015，132，42566。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号