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首页> 外文期刊>Journal of Applied Polymer Science >Development of ionic and non-ionic natural gum-based bigels: Prospects for drug delivery application
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Development of ionic and non-ionic natural gum-based bigels: Prospects for drug delivery application

机译：离子和非离子天然胶基双色胶的开发：药物递送应用的前景

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Recently, much attention has been focused on the development of gel based formulations for controlled drug delivery applications. Herein, we report the effect of the ionic (gum acacia) and the non-ionic (guar gum) gums on the properties of the bigels prepared with fluid-filled organogels. The microscopic study suggested the presence of flocculated structure in guar gum bigel, whereas, a de-flocculated structure was observed in gum acacia bigel. Infrared spectroscopy suggested the presence of polysaccharides in the bigels. The mechanical properties of the guar gum bigel were better than gum acacia bigel. The conductivity and the release properties suggested superior properties of gum acacia bigel. This indicated that the ionic nature of acacia bigel played a major role in controlled drug delivery, making it a potential bigel for desired pharmaceutical applications. (c) 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42561.
机译：最近，许多注意力集中在开发用于可控药物递送应用的基于凝胶的制剂上。在本文中，我们报道了离子性（阿拉伯树胶）和非离子性（瓜尔胶）胶对填充有液体的有机凝胶制备的双耳胶的性能的影响。显微研究表明，瓜尔豆胶中存在絮凝结构，而阿拉伯胶中则观察到了絮凝结构。红外光谱表明在比格尔斯中存在多糖。瓜尔豆胶的机械性能优于阿拉伯胶。导电性和释放性能表明胶相思树胶具有优越的性能。这表明相思树的离子性质在受控药物递送中起着重要作用，使其成为所需药物应用中的潜在树莓。 （c）2015 Wiley Periodicals，Inc. J. Appl。 Polym。科学2015，132，42561。

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