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首页> 外文期刊>Journal of Applied Polymer Science >Fabrication of PCL/beta-TCP scaffolds by 3D mini-screw extrusion printing
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Fabrication of PCL/beta-TCP scaffolds by 3D mini-screw extrusion printing

机译：通过3D小螺钉挤出印刷制造PCL / beta-TCP支架

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摘要

Scaffolds of polycaprolactone (PCL) and PCL composites reinforced with -tricalcium phosphate (-TCP) were manufactured aiming potential tissue engineering applications. They were fabricated using a three-dimensional (3D) mini-screw extrusion printing, a novel additive manufacturing process, which consists in an extrusion head coupled to a 3D printer based on the Fab@Home equipment. Thermal properties were obtained by differential scanning calorimetry and thermogravimetric analyses. Scaffolds morphology were observed using scanning electron microscopy and computed microtomography; also, reinforcement presence was observed by X-ray diffraction and the polymer chemical structure by Fourier transform infrared spectroscopy. Mechanical properties under compression were obtained by using a universal testing machine and hydrophilic properties were studied by measuring the contact angle of water drops. Finally, scaffolds with 55% of porosity and a pore size of 450 m have shown promising mechanical properties; the -TCP reinforcement improved mechanical and hydrophilic behavior in comparison with PCL scaffolds. (c) 2015 Wiley Periodicals, Inc.
机译：针对潜在的组织工程应用，制造了聚己内酯（PCL）支架和用-磷酸三钙（-TCP）增强的PCL复合材料的支架。它们是使用三维（3D）小螺杆挤出印刷工艺制造的，这是一种新颖的增材制造工艺，该工艺包括将挤出头连接到基于Fab @ Home设备的3D打印机。通过差示扫描量热法和热重分析获得热性能。使用扫描电子显微镜和计算机断层摄影术观察支架形态。另外，通过X射线衍射观察到增强物的存在，并且通过傅里叶变换红外光谱法观察到聚合物化学结构。使用通用试验机获得压缩下的机械性能，并通过测量水滴的接触角来研究亲水性能。最后，孔隙度为55％，孔径为450 m的脚手架显示出令人鼓舞的机械性能。与PCL支架相比，-TCP增强剂改善了机械和亲水性能。 （c）2015年威利期刊有限公司

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