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Basaloid skin tumours: Mimics of basal cell carcinoma

机译:胎盘皮肤肿瘤:基底细胞癌的模拟物

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This article is the second of two papers relating to the histopathological diagnosis of basaloid skin tumours and the uses of immunohistochemistry. The first paper focused on basal cell carcinoma and variants, and this paper will concentrate on tumours that may be confused with basal cell carcinoma. The basaloid tumours of the skin can be classified according to the general classification of skin tumours, including epidermal, appendageal (hair follicle and sweat gland derived) and others including cutaneous metastases. The areas of discussion concentrate on the distinction of basal cell carcinoma from basaloid squamous cell carcinoma, infiltrative basaloid tumours (desmoplastic trichoepithelioma, infiltrative basal cell carcinoma, microcystic adnexal carcinoma and eccrine epithelioma), follicular induction overlying dermatofibroma, basaloid proliferations in naevus sebaceus, trichoepithelioma, trichoblastoma, trichoepithelioma-like basal cell carcinoma, pilomatrical tumours and selected sweat gland tumours. The immunohistochemical stains that may be of use in differential diagnosis are discussed, including BerEP4, epithelial membrane antigen, CD10, bcl-2, Cam5.2, CK20, carcinoembryonic antigen and p53. ?2007 Elsevier Ltd. All rights reserved.
机译:本文是有关基底膜样皮肤肿瘤的组织病理学诊断和免疫组织化学用途的两篇论文中的第二篇。第一篇论文侧重于基底细胞癌及其变体,而本文将重点研究可能与基底细胞癌混淆的肿瘤。可以根据皮肤肿瘤的一般分类对皮肤的基底类肿瘤进行分类,包括表皮,附属物(毛囊和汗腺)和其他包括皮肤转移瘤。讨论的领域集中于基底细胞癌与基底膜鳞状细胞癌,浸润性基底膜肿瘤(增生性毛细血管上皮瘤,浸润性基底细胞癌,微囊性附件癌和内分泌上皮瘤),滤泡诱导性上皮纤维瘤,基底膜增生,基底膜样增生的区别,绒毛膜上皮瘤,毛状上皮瘤样基底细胞癌,毛发肿瘤和某些汗腺肿瘤。讨论了可能用于鉴别诊断的免疫组织化学染色,包括BerEP4,上皮膜抗原,CD10,bcl-2,Cam5.2,CK20,癌胚抗原和p53。 ?2007 Elsevier Ltd.保留所有权利。

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