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The asymmetric flagellar distribution and motility of Escherichia coli.

机译:大肠埃希氏菌的不对称分布和运动。

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Rod-shaped bacteria such as Escherichia coli divide by binary fission. They inherit an old pole from the parent cell. The new pole is recently derived from the septum. Because the chemoreceptor accumulates linearly with time on the cell pole, the old pole carries more receptors than does the new pole. Here, further evidence is provided that the old pole appears more frequently at the rear when bacteria swim. This phenomenon had been observed, yet not extensively explored in the literature. The biased swimming orientation is the consequence of the asymmetric distribution of flagella over the cell surface. On about 75% of cells, there are more flagella on the old-pole half of the cell than on the new-pole half, regardless of growth conditions. Most flagella are lateral, and few were found on the cell pole per se. The asymmetric flagellar distribution makes cells more efficient in chemotaxis. Both swimming orientation and receptor localization are components of chemotaxis, by which bacteria follow environmental stimuli. If unipolarly flagellated cells, such as the swarmer cells of Caulobacter crescentus, are regarded as 100% polar with respect to chemotaxis, E. coli is about 75%. The difference is quantitative. The peritrichous flagellation might enhance the motility and chemotaxis in the viscous environment of enteric bacteria.
机译:杆状细菌(如大肠杆菌)通过二元裂变分裂。他们从父单元继承了一个旧杆。新的极点最近来自隔垫。由于化学感受器在细胞极上随时间线性累积,因此旧极比新极携带更多的受体。在这里,进一步的证据表明,当细菌游动时,旧杆在后部的出现频率更高。已经观察到了这种现象,但是在文献中并未对其进行广泛的研究。游泳姿势的偏向是鞭毛在细胞表面上不对称分布的结果。无论生长条件如何,大约75%的细胞上,老杆一半的鞭毛要多于新杆一半的鞭毛。大多数鞭毛是侧生的,很少在细胞杆上发现。不对称的鞭毛分布使细胞趋化性更高。游泳方向和受体定位均是趋化性的成分,细菌通过该趋化性跟随环境刺激。如果将单极鞭毛细胞,例如新月形杆菌的成群细胞视为相对于趋化性为100%极性,则大肠杆菌约为75%。差异是定量的。在肠道细菌的粘性环境中,周生鞭毛可能增强运动性和趋化性。

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