...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites >Bioactive glasses: Special applications outside the skeletal system
【24h】

Bioactive glasses: Special applications outside the skeletal system

机译：生物活性玻璃：骨骼系统以外的特殊应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Bioactive glasses were invented 45 years ago and have been in clinical use since the 1980s in otology, orthopaedics and dentistry. Initially born as bioactive materials to fill bone defects, bioactive glasses expanded their biomedical suitability towards a broad spectrum of tissue engineering and therapeutic applications, and research evolution seems to witness that their potential is far from being fully exploited. Classical applications of bioactive glasses involve bone filling materials and dental implants; however, the fascinating question to be answered in the next few years is: how can bioactive glasses be useful in soft tissue regeneration and to treat diseases, such as tumours, that may affect internal organs? This review paper focuses on research that demonstrates the suitability of bioactive glasses in contact with tissues outside the skeletal system, including muscle and nerve tissue regeneration, treatment of diseases affecting sense organs (eye and ear), embolization of neoplastic tissues, cancer radiotherapy via injectable microspheres, and wound dressing. A prospect for future research is also provided, highlighting the potential associated to targeted therapy via local ion release, angiogenesis stimulation and in situ drug release, as well as the promise of biofabrication for the development of bioactive glass-containing composite constructs for organ regeneration. (C) 2015 Elsevier B.V. All rights reserved.
机译：生物活性玻璃是45年前发明的，自1980年代以来就已经在眼科，骨科和牙科领域投入临床使用。最初作为填充骨骼缺损的生物活性材料而生，生物活性玻璃将其生物医学适应性扩展到广泛的组织工程和治疗应用领域，研究进展似乎证明其潜力尚未得到充分开发。生物活性玻璃的经典应用包括骨填充材料和牙科植入物。但是，未来几年要回答的一个有趣的问题是：生物活性玻璃如何在软组织再生和治疗可能影响内部器官的疾病（例如肿瘤）中有用？本文的重点是研究表明生物活性玻璃与骨骼系统外部组织接触的适用性，包括肌肉和神经组织的再生，影响感官器官（眼和耳）的疾病的治疗，肿瘤组织的栓塞，可注射的放射疗法微球和伤口敷料。还提供了未来研究的前景，突出了通过局部离子释放，血管生成刺激和原位药物释放与靶向治疗相关的潜力，以及生物制造有望发展用于器官再生的含生物活性玻璃复合结构的前景。 （C）2015 Elsevier B.V.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号