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Substance abuse and movement disorders: Complex interactions and comorbidities

机译:物质滥用和运动障碍:复杂的相互作用和合并症

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摘要

The relationship between movement disorders and substance abuse, which we previously reviewed, is updated. We examine these relationships bidirectionally with focus on drugs of abuse that are known to cause movement disorders, as well as primary movement disorders that are associated with use and abuse of alcohol and dopaminergic medications. First, we review the movement disorders that may develop from the acute use or withdrawal of frequent drugs of abuse, including alcohol, cocaine, heroin, amphetamine and methcathinone. We then comment on the interaction between alcoholism and alcohol-responsive movement disorders, such as essential tremor and myoclonus-dystonia. Lastly, we discuss the potential for abuse of antiparkinsonian dopaminergic agents in patients with Parkinson's disease (PD).
机译:我们先前已经回顾了运动障碍与药物滥用之间的关系。我们双向研究这些关系,重点关注已知会引起运动障碍的滥用药物,以及与使用和滥用酒精及多巴胺能药物有关的原发性运动障碍。首先,我们回顾一下由于频繁使用或戒除包括酒精,可卡因,海洛因,苯丙胺和甲卡西酮在内的滥用药物而可能引起的运动障碍。然后,我们评论酒精中毒与酒精反应性运动障碍(例如原发性震颤和肌阵挛性肌张力障碍)之间的相互作用。最后,我们讨论了在帕金森氏病(PD)患者中滥用抗帕金森氏症多巴胺能药物的可能性。

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