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A place for dietary fibre in the management of the metabolic syndrome.

机译:膳食纤维在代谢综合症管理中的地位。

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PURPOSE OF REVIEW: To control the global increase of obesity and associated-metabolic syndrome, nutritional advice remains an important objective. This review discusses factors that may explain how dietary fibre would be helpful in the management of food intake, body weight and metabolic syndrome. RECENT FINDINGS: Dietary fibre could play a role in the management of the metabolic syndrome through its ability to control body weight evolution through its effect on satiety; to modulate glucose homeostasis/insulin sensitivity and to positively affect factors implicated in cardiovascular diseases. The relevance and the relative importance of these effects in control of metabolic syndrome remain unknown. Recent experimental data suggest that the modification of gut peptides - involved in appetite and glucose homeostasis - could constitute a 'metabolic relay' allowing specific (fermentable) dietary fibre to act on appetite and other components of the metabolic syndrome. SUMMARY: Dietary fibre intake may modulate parameters associated with the control of the metabolic syndrome, namely food intake (and body weight), glycemia and insulinemia, blood lipids and blood pressure. The efficacy of dietary fibre differs according to their dietary sources (fruits, legumes or cereals), but also to their specific chemical structure, responsible for their physical properties (i.e. gel forming capacity) or for their fermentation capacity in the lower part of the gut. The fermentability of dietary fibre seems important to generate specific effects on satiety and glycemia through the release of gut peptides such as glucagon-like peptide-1.
机译:审查目的:为了控制肥胖症和相关代谢综合征的全球增加,营养建议仍然是一个重要目标。这篇综述讨论了可以解释膳食纤维如何帮助控制食物摄入,体重和代谢综合症的因素。最近的发现:膳食纤维可以通过控制饱腹感来控制体重的变化,从而在代谢综合症的治疗中发挥作用。调节葡萄糖稳态/胰岛素敏感性,并积极影响与心血管疾病有关的因素。这些作用在代谢综合征控制中的相关性和相对重要性仍然未知。最近的实验数据表明,肠肽的修饰-参与食欲和葡萄糖稳态-可能构成“代谢传递”,使特定(可发酵)膳食纤维作用于食欲和代谢综合征的其他成分。摘要:膳食纤维的摄入量可能会调节与代谢综合征控制相关的参数,即食物摄入量(和体重),血糖和胰岛素血症,血脂和血压。膳食纤维的功效因其饮食来源(水果,豆类或谷物)而异,还取决于其特定的化学结构,这些化学结构决定了其物理性质(即凝胶形成能力)或肠道下部的发酵能力。通过释放肠肽(如胰高血糖素样肽-1),膳食纤维的发酵性对于产生饱腹感和血糖的特定作用似乎很重要。

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