Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

Mieda M; Yanagisawa M

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Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

机译：睡眠，进食和神经肽：orexin和orexin受体的作用。

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RECENT STUDIES USING MOLECULAR GENETICS IN MICE AND DOGS, AS WELL AS HISTOPATHOLOGICAL ANALYSES OF HUMAN DISEASE, HAVE COME TO THE SAME CONCLUSION: the human sleep disorder narcolepsy is caused by failure of signaling mediated by orexin (hypocretin) neuropeptides. These and other findings strongly suggest that the orexin system plays a critical role in sleep/wake regulation. In addition, the orexin system may link energy homeostasis to the regulation of sleep/wake cycles.

机译：最近在小鼠和犬类中使用分子遗传学以及人类疾病的组织病理学分析得出的相同结论是：人类睡眠障碍发作性睡病是由食欲素（促肾上腺素）神经肽介导的信号传导失败引起的。这些和其他发现强烈表明，食欲素系统在睡眠/唤醒调节中起关键作用。另外，食欲素系统可以将能量稳态与睡眠/苏醒周期的调节联系起来。

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《Current Opinion in Neurobiology》 |2002年第3期|共7页
作者
Mieda M; Yanagisawa M;
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正文语种 eng
中图分类生理学;
关键词
Neuropeptides; Sleep brand of diphenhydramine hydrochloride; receptor; Feeding; 神经肽类;

机译：神经肽;盐酸苯海拉明的睡眠品牌;受体;进食;神经肽类;

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1. Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors. [J] . Mieda M, Yanagisawa M Current Opinion in Neurobiology . 2002,第3期

机译：睡眠，进食和神经肽：orexin和orexin受体的作用。
2. The role of neuropeptide Y, orexins, cocaine and amphetamine-related transcript, cholecystokinin, amylin and leptin in the regulation of feeding in fish [J] . Volkoff H Comparative biochemistry and physiology, Part A. Molecular and integrative physiology . 2006,第3期

机译：神经肽Y，食欲素，可卡因和苯丙胺相关转录本，胆囊收缩素，胰岛淀粉样多肽和瘦素在鱼类摄食调节中的作用
3. Role of leptin in the control of feeding of goldfish Carassius auratus: interactions with cholecystokinin, neuropeptide Y and orexin A, and modulation by fasting. [J] . Volkoff H, Joy Eykelbosh A, Ector Peter R Brain research . 2003,第1a2期

机译：瘦素在金鱼Car鱼摄食控制中的作用：与胆囊收缩素，神经肽Y和食欲素A的相互作用以及禁食调节。
4. A novel hypothalamic peptide, neuroendocrineregulatory peptide-2, regulates feeding behavior via the orexin system in the hypothalamus [C] . Koji Toshinai, Hideki Yamaguchi, Haruaki Kageyama Japanese peptide symposium . 2011

机译：一种新的下丘脑肽，神经内部病症肽-2，通过下丘脑中的orexin系统调节饲养行为
5. Postnatal Developmental Changes of the Orexin System and Its Potential Role in Neurogenic Hypertension in a Rat Model of Essential Hypertension [D] . Barnett, Savannah. 2019

机译：orexin系统的产后发育变化及其在原发性高血压大鼠模型中神经源性高血压的潜在作用
6. The Dual Orexin Receptor Antagonist Almorexant Induces Sleep and Decreases Orexin-Induced Locomotion by Blocking Orexin 2 Receptors [O] . Géraldine M. Mang, Thomas Dürst, Hugo Bürki, 2012

机译：双重Orexin受体拮抗剂Almorexant通过阻断Orexin 2受体诱导睡眠并降低Orexin诱导的运动。
7. Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior [O] . Sakurai Takeshi, Amemiya Akira, Ishii Makoto, 1998

机译：食欲素和食欲素受体：下丘脑神经肽和G蛋白偶联的受体，调节喂养行为的一个家庭。
8. Detection of Orexin A Neuropeptide in Biological Fluids Using a Zinc Oxide Field Effect Transistor. [R] . Hagen, J., Lyon, W., Chushak, Y., 2012

机译：利用氧化锌场效应晶体管检测生物流体中的食欲素a神经肽。

Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

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