The many faces of p75(NTR).

Hempstead BL

首页> 外文期刊>Current Opinion in Neurobiology >The many faces of p75(NTR).

【24h】

The many faces of p75(NTR).

机译：p75（NTR）的许多面孔。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The neurotrophins utilize a complex receptor system consisting of Trk receptor tyrosine kinases and the structurally unrelated tumor necrosis factor receptor family member, p75(NTR), to confer diverse and sometimes opposing biological actions. The recent identification of selective ligands for p75(NTR), novel isoforms of this receptor, as well as new signaling partners, suggest that the numerous biological actions of the neurotrophins via p75(NTR) may reflect selectivity of ligand-receptor interactions and intracellular adaptor protein recruitment.

机译：神经营养蛋白利用由Trk受体酪氨酸激酶和结构上无关的肿瘤坏死因子受体家族成员p75（NTR）组成的复杂受体系统，赋予多种生物作用，有时甚至是相反的生物学作用。最近鉴定的p75（NTR）选择性配体，该受体的新亚型以及新的信号传导伙伴表明，神经营养蛋白通过p75（NTR）的多种生物学作用可能反映了配体-受体相互作用和细胞内衔接子的选择性蛋白质募集。

著录项

来源
《Current Opinion in Neurobiology》 |2002年第3期|共8页
作者
Hempstead BL;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生理学;
关键词
p75 neurotrophin receptor; novel; Intracellular;

机译：p75神经营养蛋白受体;新颖;细胞内;

相似文献

外文文献
中文文献
专利

1. P75~(NTR) expression and nuclear localization of p75~(NTR) intracellular domain in spiral ganglion Schwann cells following deafness correlate with cell proliferation [J] . Provenzano M.J., Minner S.A., Zander K., Molecular and cellular neurosciences . 2011,第4期

机译：耳聋后螺旋神经节雪旺细胞中p75〜（NTR）的表达和p75〜（NTR）细胞内结构域的核定位与细胞增殖相关
2. Temporally restricted death and the role of p75 NTR NTR as a survival receptor in the developing sensory nervous system [J] . Cheng Irene, Jin Lucy, Rose Lucy C., Developmental neurobiology . 2018,第7期

机译：暂时限制死亡和P75 NTR NTR的作用作为发育中神经系统中的生存受体
3. Effects of p75 NTR NTR deficiency on cholinergic innervation of the amygdala and anxiety‐like behavior [J] . Busch Ruben, Baldus Marian, Vogt Miriam A., Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2017,第3期

机译：P75 NTR NTR缺乏对杏仁核和焦虑的行为的胆碱能物质的影响
4. Molecular modeling of the interaction of neurotrophins with the P75~NTR common neurotrophin receptor [C] . Igor L.Shamovsky, Gregory M.Ross, Richard J.Riopelle, Annual international high performance computing systems and applications symposium . 2000

机译：神经营养素与P75〜NTR常见神经营养素受体相互作用的分子模拟
5. Prenatal cocaine dysregulates BDNF--TrkB and p75(NTR) signaling in the hippocampus and prefrontal cortex of adolescent. [D] . Stucky, Andres Wood. 2013

机译：产前可卡因在青少年海马和前额叶皮层中调节BDNF-TrkB和p75（NTR）信号。
6. Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells [O] . Dan Duc Pham, Céline Bruelle, Hai Thi Do, 2019

机译：Caspase-2和p75神经营养蛋白受体（p75NTR）参与肝细胞SREBP和脂质基因的调控
7. MP28-20 P75 NTR ANTAGONISM DECREASED INFLAMMATORY RESPONSE OF UROTHELIAL AND SMOOTH MUSCLE CELLS TO LIPOPOLYSACCHARIDE [O] . Benjamin Desormeau*, Laura Yan, Abubakr Mossa, 2020

机译：MP28-20 P75 NTR拮抗作用下降尿液和平滑肌细胞对脂多糖的炎症反应

The many faces of p75(NTR).

摘要

著录项

相似文献

相关主题

期刊订阅