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Current management of overactive bladder.

机译:目前对膀胱过度活动症的治疗。

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PURPOSE OF REVIEW: The concept of overactive bladder has helped us address the problem of urgency and urge incontinence from a symptomatic perspective. In this review, we provide a critical summary of clinically relevant recent publications, focusing in particular on advances in our understanding of assessment methods and therapeutic interventions for overactive bladder in women. RECENT FINDINGS: According to current definitions, the prevalence of overactive bladder in western nations is now estimated as 13.0%. Although the prevalence increases with age, the symptoms of overactive bladder may follow a relapsing and remitting course. There has been a proliferation of validated symptom and quality of life measures and increasing sophistication in the analysis of bladder diaries. The role of urodynamics in the evaluation of urgency remains uncertain, with many trials showing limited benefit as a preoperative investigation. Fluid restriction and bladder retraining remain important first-line interventions.Many new anticholinergic medications have been licensed, with limited benefits compared with existing preparations. Intravesical botulinum toxin has become a popular alternative for patients who fail oral therapies. SUMMARY: Although there have been few important therapeutic innovations, recent publications have led to greater sophistication in assessment methods and a clearer understanding of the role of existing interventions.
机译:审查目的:膀胱过度活动症的概念帮助我们从症状的角度解决了尿急和急迫性尿失禁的问题。在这篇综述中,我们提供了有关临床相关近期出版物的重要摘要,尤其着重于我们对女性膀胱过度活动症的评估方法和治疗干预措施的理解的进步。最新发现:根据目前的定义,据估计西方国家膀胱过度活动症的患病率为13.0%。尽管患病率随年龄增长而增加,但膀胱过度活动的症状可能遵循复发和缓解的过程。在膀胱日记的分析中,已证实的症状和生活质量的措施正在激增,复杂性也在增加。尿动力学在尿急性评估中的作用尚不确定,许多试验显示术前检查的获益有限。限制液体和膀胱再培训仍然是重要的一线干预措施。许多新的抗胆碱能药物已获许可,与现有制剂相比,其收益有限。膀胱内肉毒杆菌毒素已成为口服治疗失败的患者的替代方法。简介:尽管很少有重要的治疗创新,但最近的出版物导致评估方法更加成熟,对现有干预措施的作用有了更清晰的了解。

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