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首页> 外文期刊>Current Opinion in Neurobiology >Motoring ahead with rodents.
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Motoring ahead with rodents.

机译:驱赶啮齿动物。

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摘要

How neural circuits underlie the acquisition and control of learned motor behaviors has traditionally been explored in monkeys and, more recently, songbirds. The development of genetic tools for functional circuit analysis in rodents, the availability of transgenic animals with well characterized phenotypes, and the relative ease with which rats and mice can be trained to perform various motor tasks, make rodents attractive models for exploring the neural circuit mechanisms underlying the acquisition and production of learned motor skills. Here we discuss the advantages and drawbacks of this approach, review recent trends and results, and outline possible strategies for wider adoption of rodents as a model system for complex motor learning.
机译:传统上已经在猴子和最近的鸣禽中研究了神经回路如何构成习得的运动行为的获取和控制的基础。啮齿类动物功能电路分析的遗传工具的开发,具有良好表型的转基因动物的可用性以及可以训练大鼠和小鼠执行各种运动任务的相对容易性,这使啮齿动物成为了探索神经回路机制的诱人模型学习和掌握运动技能的基础。在这里,我们讨论了这种方法的优缺点,回顾了最近的趋势和结果,并概述了将啮齿类动物广泛用作复杂运动学习的模型系统的可能策略。

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