Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold

首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold

【24h】

Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold

机译：七叶β-螺旋桨折叠的Burkholderia pseudomallei和紫杉杆菌的新型凝集素的特征

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Burkholderia pseudomallei and Chromobacterium violaceum are bacteria of tropical and subtropical soil and water that occasionally cause fatal infections in humans and animals. Microbial lectins mediate the adhesion of organisms to host cells, which is the first phase in the development of infection. Here we report the discovery of two novel lectins from the above-mentioned bacteria - BP39L and CV39L. The crystal structures revealed that the lectins possess a seven-bladed beta-propeller fold. Functional studies conducted on a series of oligo- and polysaccharides confirmed the preference of BP39L for mannosylated saccharides and CV39L for rather more complex polysaccharides with a monosaccharide preference for beta-L-fucose. The presented data indicate that the proteins belong to a currently unknown family of lectins. (C) 2019 Elsevier B.V. All rights reserved.

机译：Burkholderia pseudomallei和vircobacterium violaceum是热带和亚热带土壤和水的细菌，偶尔会导致人类和动物的致命感染。微生物凝集素介导生物体对宿主细胞的粘附，这是感染发育中的第一阶段。在这里，我们报告了来自上述细菌 - BP39L和CV39L的两种新建凝集素的发现。晶体结构透露，凝集素具有七叶片β-螺旋桨折叠。在一系列寡糖和多糖上进行的功能性研究证实了BP39L对甘露糖苷化的糖和CV39L的偏好，而是具有对β-L-粘膜的单糖偏好的相当复杂的多糖。呈现的数据表明蛋白质属于目前未知的凝集家族。（c）2019 Elsevier B.v.保留所有权利。

著录项

来源
《International Journal of Biological Macromolecules: Structure, Function and Interactions》 |2020年第2020期|共12页
作者

展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生物大分子的结构和功能;
关键词
Lectin; Burkholderia pseudomallei; Chromobacterium violaceum; Protein structure; Seven-bladed beta-propeller fold;

机译：章节;Burkholderia pseudomallei;紫杉杆菌;蛋白质结构;七叶β-螺旋桨折叠;

相似文献

外文文献
中文文献
专利

1. Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold [J] . International Journal of Biological Macromolecules: Structure, Function and Interactions . 2020,第期

机译：七叶β-螺旋桨折叠的Burkholderia pseudomallei和紫杉杆菌的新型凝集素的特征
2. Production and properties of the native Chromobacterium violaceum fucose-binding lectin (CV-IIL) compared to homologous lectins of Pseudomonas aeruginosa (PA-IIL) and Ralstonia solanacearum (RS-IIL) [J] . Keren Zinger-Yosovich, Dvora Sudakevitz, Anne Imberty, Microbiology . 2006,第2期

机译：与铜绿假单胞菌（PA-IIL）和Ralstonia solanacearum的同源凝集素（CV-IIL）和Ralstonia solanacearum（Rs-Iil）的同源凝集素（CV-IIL）的生产和性质进行紫杉曲膜结合凝集素（CV-IIL）
3. Phagocyte NADPH Oxidase, but Not Inducible Nitric Oxide Synthase, Is Essential for Early Control of Burkholderia cepacia and Chromobacterium violaceum Infection in Mice [J] . Brahm H. Segal, Li Ding, Steven M. Holland Infection and immunity . 2003,第1期

机译：吞噬细胞NADPH氧化酶，但不是诱导型一氧化氮合酶，对于早期控制洋葱伯克霍尔德菌和小鼠紫色杆菌感染至关重要。
4. Structural Analyses of Lipid A from Burkholderia pseudomallei and Burkholderia thailandensis by Mass Spectrometry [C] . Ravi Chandran Reddy Alla, Michael Bechill, Susan Salari, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：来自Burokholderia pseudomallei和Burkhowderia泰国的脂质A的结构分析质谱法
5. Biochemical and genomic characterization of Chromobacterium violaceum strains isolated from the Tennessee Copper Basin. [D] . Gaston, Antoinette. 2010

机译：从田纳西州铜盆地分离的紫罗兰色杆菌菌株的生化和基因组学表征。
6. Phagocyte NADPH Oxidase but Not Inducible Nitric Oxide Synthase Is Essential for Early Control of Burkholderia cepacia and Chromobacterium violaceum Infection in Mice [O] . Brahm H. Segal, Li Ding, Steven M. Holland 2003

机译：吞噬细胞NADPH氧化酶但不是诱导型一氧化氮合酶对于早期控制洋葱伯克霍尔德菌和小鼠紫色杆菌感染至关重要。
7. Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed β-propeller fold [O] . Petra Sýkorová, Jitka Novotná, Gabriel Demo, 2020

机译：七叶β-螺旋桨折叠伯克德列风症假调子和紫杉杆菌的新型凝集素的特征
8. Genomic Diversity of Burkholderia pseudomallei Clinical Isolates: Subtractive Hybridization Reveals a Burkholderia mallei-Specific Prophage in B. pseudomallei 1026b. [R] . DeShazer, D. 2004

机译：Burkholderia pseudomallei临床分离株的基因组多样性：消减杂交揭示了B. pseudomallei 1026b中的伯克霍尔德氏菌特异性原噬菌体。

相关主题

Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold

摘要

著录项

相似文献

相关主题

期刊订阅