...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Chitosan surface modified electrospun poly(epsilon-caprolactone)/carbon nanotube composite fibers with enhanced mechanical, cell proliferation and antibacterial properties
【24h】

Chitosan surface modified electrospun poly(epsilon-caprolactone)/carbon nanotube composite fibers with enhanced mechanical, cell proliferation and antibacterial properties

机译：壳聚糖表面改性ElectrometOM聚（ε-己内酯）/碳纳米管复合纤维，具有增强的机械，细胞增殖和抗菌性能

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The surface modification is one of the most effective methods to improve the bioactivity and cell affinity effect of electrospun poly(epsilon-caprolactone) (PCL) fibers. In the present study, chitosan (CS), a cationic polysaccharide, was used to modify the surface of electrospun PCL fibers. To obtain strong interaction between CS and PCL fibers, negatively charged PCL fibers were prepared by the incorporation of acid treated carbon nanotubes (CNTs) into the fibers. In this way, the positively charged chitosan could be immobilized onto the surface of PCL fibers tightly by the electrostatic attraction. Besides, the incorporation of CNTs could significantly improve the mechanical strength of electrospun PCL fibers even after the CS modification, which guaranteed their usability in practical applications. The CS modification could effectively improve the wettability and bioactivity of electrospun PCL fibers. Cultivation of L929 fibroblast cells on the obtained fibers and the antibacterial activity were both evaluated to discuss the influence of chitosan modification. The results indicated that this modification could enhance the cell proliferation and antibacterial ability in comparison to the non -modified groups. (C) 2017 Elsevier B.V. All rights reserved.
机译：表面改性是提高Electur纺聚（ε-己内酯）（PCL）纤维的生物活性和细胞亲和力效果的最有效方法之一。在本研究中，壳聚糖（CS）是阳离子多糖，用于改变Electrom淘PCL纤维的表面。为了获得Cs和PCL纤维之间的强相互作用，通过将酸处理的碳纳米管（CNT）掺入纤维中来制备带负电的PCL纤维。以这种方式，通过静电吸引力将带正电的壳聚糖紧紧地固定在PCL纤维的表面上。此外，即使在CS改性之后，CNT的掺入也可以显着提高Electrom淘PCL纤维的机械强度，这保证了它们在实际应用中的可用性。 CS改性可以有效提高Electromun PCL纤维的润湿性和生物活性。在所得纤维上培养L929成纤维细胞和抗菌活性均评估壳聚糖改性的影响。结果表明，与未涂覆的基团相比，该修饰可以增强细胞增殖和抗菌能力。 （c）2017年Elsevier B.V.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号