Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity.

Khalil NS

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Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity.

机译：高效合成新型1,2,4-三唑熔融环状和21-28元的大环和/或Lariat Macrocyclic OxaazathaaZaaZia冠状化合物，具有潜在的抗微生物活性。

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Versatile simple efficient routes with good to excellent yields towards different functionalized 1,omega-bis(1,2,4-triazoles), 21-28 membered 1,2,4-triazole fused macrocyclic and/or lariat macrocyclic oxaazathia crown Schiff bases and/or amines have been investigated. Antimicrobial screening of some selected compounds revealed different inhibitory effects against Aspergillus fumigatus RCMB 002008 (1), Penicillium italicum RCMB 001018 (1), Syncephalastrum racemosum RCMB 016001 Candida albicans RCMB 005003, Staphylococcus aureus RCMB 106-001 (1), Pseudomonas aeruginosa RCMB 102-002, Bacillus subtilis RCMB 101-001 and Escherichia coli RCMB 103-001.

机译：多功能简单的高效途径，良好的官能团到不同的官能化1，ω-bis（1,2,4-三唑），21-28元1,2,4-三唑融合的大环和/或Lariat macrocclic oxaazatha冠秀基 /或已经调查了胺。一些选定化合物的抗菌筛查显示不同抑制作用对Aspergillus fumigatus rcmb 002008（1），青霉斜率rcmb 001018（1），综合血症术rcmb 016001念珠菌rcmb 005003，金黄色葡萄球菌rcmb 106-001（1），假单胞菌铜绿假单胞菌rcmb 102 -002，枯草芽孢杆菌RCMB 101-001和大肠杆菌RCMB 103-001。

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《European Journal of Medicinal Chemistry: Chimie Therapeutique》 |2010年第11期|共13页
作者
Khalil NS;
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Regional Center for Food and Feed Agricultural Research Center 9 El Gamaa St. PO Box 588 Orman Giza Egypt.;

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1. Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity. [J] . Khalil NS European Journal of Medicinal Chemistry: Chimie Therapeutique . 2010,第11期

机译：有效合成新型的1,2,4-三唑稠合的无环和21-28元大环和/或套索大环含氮杂草冠化合物，具有潜在的抗菌活性。
2. Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity. [J] . Khalil NS European Journal of Medicinal Chemistry: Chimie Therapeutique . 2010,第11期

机译：高效合成新型1,2,4-三唑熔融环状和21-28元的大环和/或Lariat Macrocyclic OxaazathaaZaaZia冠状化合物，具有潜在的抗微生物活性。
3. Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity. [J] . Khalil NS European Journal of Medicinal Chemistry: Chimie Therapeutique . 2010,第11期

机译：高效合成新型1,2,4-三唑熔融环状和21-28元的大环和/或Lariat Macrocyclic OxaazathaaZaaZia冠状化合物，具有潜在的抗微生物活性。
4. An convenient and efficient synthesis of bridged bis-phenanthroline macrocyclic compounds [C] . Wen-Jwu Wang International symposium for Chinese organic chemists . 2000

机译：方便，高效地合成桥接双菲咯啉大循环化合物
5. Synthesis, spectral characterization and microbiological studies of Co(II), Ni(II) and Cu(II) complexes with some novel 20-membered macrocyclic hydrazino-1,2,4-triazole Schiff bases [O] . Prakash Gouda Avaji, Sangamesh Amarappa Patil 2009

机译：用一些新的20元宏环水肼-1,2,4-Tri唑Schiff碱基合成，Ni（II），Ni（II），Ni（II）和Cu（II）复合物的合成，光谱表征及微生物研究

Efficient synthesis of novel 1,2,4-triazole fused acyclic and 21-28 membered macrocyclic and/or lariat macrocyclic oxaazathia crown compounds with potential antimicrobial activity.

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