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Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus

机译:大麻苜蓿和木兰绳发现的Terpenes的药用性质

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Cannabaceae plants Cannabis sativa L and Humulus lupulus L. are rich in terpenes both are typically comprised of terpenes as up to 3-5% of the dry-mass of the female inflorescence. Terpenes of cannabis and hops are typically simple mono- and sesquiterpenes derived from two and three isoprene units, respectively. Some terpenes are relatively well known for their potential in biomedicine and have been used in traditional medicine for centuries, while others are yet to be studied in detail. The current, comprehensive review presents terpenes found in cannabis and hops. Terpenes' medicinal properties are supported by numerous in vitro, animal and clinical trials and show anti-inflammatory, antioxidant, analgesic, anticonvulsive, antidepressant, anxiolytic, anticancer, antitumor, neuroprotective, antimutagenic, anti-allergic, antibiotic and anti-diabetic attributes, among others. Because of the very low toxicity, these terpenes are already widely used as food additives and in cosmetic products. Thus, they have been proven safe and well-tolerated. (C) 2018 Elsevier Masson SAS. All rights reserved.
机译:Canabaceae植物大麻苜蓿L和Humulus Lupulus L.富含萜烯,均通常由萜烯组成,其含量高达雌性花序的干质量的3-5%。大麻和啤酒花的Terpenes通常是衍生自两个和三个异戊二烯单元的简单单萜和倍半乙烯单位。一些Terpenes在生物医学中的潜力相对众所周知,并且已在传统医学中用于几个世纪,而其他人则尚未详细研究。目前的全面审查显示了大麻和啤酒花中的萜烯。 Terpenes的药用特性得到了许多体外,动物和临床试验的支持,并显示出抗炎,抗氧化剂,镇痛,抗抑化,抗抑郁药,抗抑郁剂,抗癌,抗肿瘤,神经保护,抗毒性,抗过敏,抗生素和抗糖尿病属性其中。由于毒性很低,这些萜烯已被广泛用作食品添加剂和化妆品。因此,他们已被证明安全且耐受良好。 (c)2018年Elsevier Masson SAS。版权所有。

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