Synthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates

Munneke Stefan; Hill Jaimé C.; Timmer Mattie S. M.; Stocker Bridget L.

首页> 外文期刊>European journal of organic chemistry >Synthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates

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Synthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates
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机译： n n - 和 O O-甲氧氧基胺接头，用于合成血糖癌的合成和 n n - 和 O o -methyloxyamine接头，用于合成糖醌缀合物
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> A comparison of the merits of N ‐ and O ‐methyloxyamines as linkers for carbohydrates is presented for the first time. In particular, optimized synthetic routes for each linker type are given, and the ease of glycan conjugation is described. The hydrolytic stabilities of the respective oxyamine glycoconjugates under a variety of different conditions are reported. This provides insight into the factors that influence hydrolysis rates, and sheds light on the acid‐catalysed hydrolysis mechanism. 展开▼

机译： > n 的优点的比较 - 以及 o 展开▼

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来源
《European journal of organic chemistry》 |2017年第25期|共7页

作者
Munneke Stefan; Hill Jaimé C.; Timmer Mattie S. M.; Stocker Bridget L.;
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作者单位

School of Chemical and Physical SciencesVictoria University of WellingtonP. O. Box 600 Wellington New Zealand;

School of Chemical and Physical SciencesVictoria University of WellingtonP. O. Box 600 Wellington New Zealand;

School of Chemical and Physical SciencesVictoria University of WellingtonP. O. Box 600 Wellington New Zealand;

School of Chemical and Physical SciencesVictoria University of WellingtonP. O. Box 600 Wellington New Zealand;

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原文格式 PDF

正文语种 eng

中图分类有机化学;

关键词
Carbohydrates; Glycoconjugates; Conjugation; Oxyamines; Hydrolysis; Reaction mechanisms;

机译：碳水化合物;糖凝固物;缀合;氧胺;水解;反应机制;

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外文文献

1. Synthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates [J] . Munneke Stefan, Hill Jaimé C., Timmer Mattie S. M., European journal of organic chemistry . 2017,第25期

机译： n n - 和 O O-甲氧氧基胺接头，用于合成血糖癌的合成和 n n - 和 O o -methyloxyamine接头，用于合成糖醌缀合物

2. Fluorine at the C5 Position of 2′‐Deoxyuridine Enhances Repair of a OO ^{44 ‐Methyl Adduct by OO ^{66 ‐Alkylguanine DNA Alkyltransferases}} [J] . Sacre Lauralicia, Wilds Christopher J. European journal of organic chemistry . 2017,第20期

机译：2'-脱氧尿苷的C5位置的氟增强了A O o ^{4 4 - 通过 o o ^{6”/sup viley"> 6- alkylguanine DNA烷基转移酶}}

3. Synthesis of PCLPCL ‐branched P(MMAP(MMA ‐ coco ‐ HEMAHEMA ) to toughen electrospun PLLAPLLA fiber membrane [J] . Jiang Suchen, Liu Huanchao, Zhang Xue, Polymers for advanced technologies . 2018,第1期

机译：综合 pcl pcl --branched p（mma p（mma - co co - hema hema）来强化electrome plla plla纤维膜

4. Catalytic Asymmetric Synthesis 2nd Edition. By Iwao Ojima (Editor)Wiley-VCH: New York (http://www.wiley.com/). 2000. Pages: XIV 864 Pages Hardcover. Price: 169.- Euro / 330.54 DM / 294.- SFR. ISBN: 0-471-29805-0 [O] . 2001

机译：催化不对称合成第二版。奥利马（Iwao Ojima）（编辑）Wiley-VCH：纽约（http://www.wiley.com/）。 2000。页数：XIV864页精装。价格：169.-欧元/330.54 DM / 294.- SFR。国际标准书号（ISBN）：0-471-29805-0

5. Measurement of dijet kT in p–Pb collisions at sNN=5.02 TeV [O] . Adam, J., Conesa Balbastre, G., Faivre, J., 2015

机译：dijet的测量 k T 在p–Pb中 s NN = 5.02 TeV

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Synthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of GlycoconjugatesSynthesis and Hydrolytic Stability of NN ‐ and OO ‐Methyloxyamine Linkers for the Synthesis of Glycoconjugates

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