• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European journal of organic chemistry >Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations
【24h】

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

机译：改善C = N键减少（环戊二烯酮）铁复合物：范围和限制

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Herein, we broaden the application scope of (cyclopentadienone) iron complexes 1 in C=N bond reduction. The catalytic scope of pre-catalyst 1b, which is more active than the "Kn?lker complex" (1a) and other members of its family, has been expanded to the catalytic transfer hydrogenation (CTH) of a wider range of aldimines and ketimines, either pre-isolated or generated in situ. The kinetics of 1b-promoted CTH of ketimine S1 were assessed, showing a pseudo-first order profile, with TOF = 6.07 h~(-1) at 50 % conversion. Moreover, the chiral complex 1c and its analog 1d were employed in the enantioselective reduction of ketimines and reductive amination of ketones, giving fair to good yields and moderate enantioselectivity.
机译：在此，我们拓宽（环戊二烯酮）铁复合物1中的施用范围1中的C = N键减少。 预催化剂1b的催化范围比“kn？kner络合物”（1a）和其家族成员更活跃，已经扩展到较广泛的醛胺和酮亚胺的催化转移氢化（CTH） ，预先孤立或原位生成。 评估1B促进的酮酮S1的动力学，显示伪第一订单曲线，TOF = 6.07h〜（-1）转化。 此外，采用手性复合物1C及其模拟1D在酮菊花和酮的还原胺化的对映选择性的减少中，使良好的产量和中度对映选择性相结合。

著录项

  • 来源
  • 作者

    Mattia Cettolin; Xishan Bai; Dennis Lübken; Marco Gatti; Sofia Vailati Facchini; Umberto Piarulli; Luca Pignataro; Cesare Gennari;

  • 作者单位

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

    Università degli Studi dell'Insubria Dipartimento di Scienza e Alta Tecnologia Via Valleggio 11 - 22100 Como Italy;

    Università degli Studi dell'Insubria Dipartimento di Scienza e Alta Tecnologia Via Valleggio 11 - 22100 Como Italy;

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

    Università degli Studi di Milano Dipartimento di Chimica Via C. Golgi 19 - 20133 Milan Italy;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 有机化学;
  • 关键词

    Transfer hydrogenation; Iron; Amination; Imines; Asymmetric catalysis;

    机译：转移氢化;铁;胺化;亚胺;不对称催化;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号