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Capillary electrophoresis-driven synthesis of water-soluble CdTe quantum dots in nanoliter scale

机译:毛细管电泳驱动的纳米尺度水溶性CdTe量子点的合成

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'Green nanotechnology' is a term used for the design of nanomaterials and processes that reduce or eliminate the use and/or generation of hazardous substances. In this paper, a capillary electrophoresis (CE)-driven synthesis of CdTe quantum dots (QDs) and their subsequent conjugation with a metal-binding protein metallothionein (isofom MT1) is reported. Even though the toxic materials (cadmium and potassium borohydride) were used for synthesis, the proposed method can be labeled as 'environmentally friendly' because the whole process (synthesis of QDs and MT1 conjugation) was carried out under mild conditions: ultra-low volume (nanoliter scale), relatively low temperature (50 degrees C), atmospheric pressure, and completed in a short time (under 90 s). Prepared QDs were also characterized by classical fluorescence spectroscopy and transmission electron microscopy. This study opens up new possibilities for the utilization of classical CE in the synthesis of nanoparticles and on-line labeling of biomolecules in the nanoliter scale in short period of time.
机译:“绿色纳米技术”是用于设计纳米材料和过程的术语,减少或消除危险物质的使用和/或产生。本文报道了一种毛细管电泳(CE)的CDTE量子点(QDS)的合成及其随后与金属结合蛋白质金属硫硫蛋白(ISOFOM MT1)的缀合。即使有毒物质(硼氢化钾)用于合成,所提出的方法也可以标记为“环保”,因为在温和条件下进行全过程(QDS和MT1缀合的合成):超低量(纳米升降型),相对较低的温度(50℃),大气压,并在短时间内完成(在90秒以下)。制备的QDS的特征在于经典荧光光谱和透射电子显微镜。本研究开辟了在短时间内利用纳米粒子的合成和在纳米型尺度的生物分子的合成中的经典Ce的新可能性。

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