• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nanotechnology >Ultrasensitive, highly selective, and real-time detection of protein using functionalized CNTs as MIP platform for FOSPR-based biosensor
【24h】

Ultrasensitive, highly selective, and real-time detection of protein using functionalized CNTs as MIP platform for FOSPR-based biosensor

机译：使用官能化CNT的超敏感，高度选择性和实时检测蛋白质作为基于FOSPR的生物传感器的MIP平台

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A facile approach is presented for the detection of bovine serum albumin (BSA), based on fiber optic surface plasmon resonance (FOSPR) combined with molecular imprinting (MI). The probe is fabricated by exploiting the plasmonic property of silver thin film and vinyl-functionalised carbon nanotube-based MIP platform. BSA template molecules are imprinted on the MIP layer coated over multi-walled carbon nanotubes to ensure high specificity of the probe in the interfering environments. In addition, FOSPR endorses the sensor capability of real-time and remote sensing along with very high sensitivity due to the use of nanostructured MI platform. The response of the probe is considered in terms of the absorbance spectrum recorded for various concentrations of BSA. The sensor shows a wide dynamic range of 0-350 ng l(-1) with a considerably linear response up to 100 ng l(-1) in the peak absorbance wavelength with BSA concentration. A highest sensitivity of 0.862 nm per ng l(-1) is achieved for the lowest concentration of BSA and it decreases with the increase in BSA concentration. The performance of the present sensor is compared with those reported in the literature in terms of the limit of detection. It is found that the probe possesses a lowest LOD of 0.386 ng l(-1) in addition to other advantages such as real-time online monitoring, high sensitivity, high specificity, and remote sensing.
机译：提出了一种基于纤维光学表面等离子体共振（FOSPR）与分子印迹（MI）组合的牛血清白蛋白（BSA）的容易方法。通过利用银薄膜和乙烯基 - 官能化碳纳米管的MIP平台的抗议性，制造探针。 BSA模板分子在涂覆在多壁碳纳米管上的壁层上印迹，以确保干扰环境中的探针的高特异性。此外，由于使用纳米结构MI平台，FOSPR还具有实时和遥感的传感器能​​力以及非常高的灵敏度。根据针对各种浓度的BSA记录的吸光度谱来考虑探针的响应。该传感器显示出0-350ng L（-1）的宽动态范围，其具有相当线性的响应，其峰值吸光度波长在具有BSA浓度的峰值吸光度波长中。为最低浓度的BSA浓度达到每NG L（-1）的最高敏感性，并且随着BSA浓度的增加而降低。将本发明传感器的性能与文献中的检测极限进行比较。发现探头除了其他优点之外，探头还具有0.386 ng L（-1）的最低床位，例如实时在线监测，高灵敏度，高特异性和遥感。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号